hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01452.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EPN2 | Epsin-2 (EPS-15-interacting protein 2) | 5 | UniProt NCBI |
| NUMBL | Numb-like protein (Numb-related protein) (Numb-R) | 5 | UniProt NCBI |
| CRTC2 | CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2) | 5 | UniProt NCBI |
| CRTC3 | CREB-regulated transcription coactivator 3 (Transducer of regulated cAMP response element-binding protein 3) (TORC-3) (Transducer of CREB protein 3) | 5 | UniProt NCBI |
| PKP2 | Plakophilin-2 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9707616 | 0.0130168285242 | 0.4 | CRTC2 CRTC3 | Heme signaling |
| REAC:R-HSA-2151201 | 0.0170393864121 | 0.4 | CRTC2 CRTC3 | Transcriptional activation of mitochondrial biogenesis |
| REAC:R-HSA-400253 | 0.0275944536635 | 0.4 | CRTC2 CRTC3 | Circadian Clock |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CRTC2 | CRTC3 | 0.994 | 0.086 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| CRTC2 | EPN2 | 0.987 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| EPN2 | PKP2 | 0.987 | hein_WMM bioplex3_WMM WMM_only boldt_WMM | |
| CRTC3 | EPN2 | 0.984 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| NUMBL | EPN2 | 0.981 | hein_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| CRTC2 | NUMBL | 0.974 | 0.132 | hein_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
| CRTC2 | PKP2 | 0.966 | 0.082 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only boldt_WMM |
| CRTC3 | PKP2 | 0.893 | 0.13 | hein_WMM bioplex3_WMM youn_WMM WMM_only boldt_WMM |
| NUMBL | PKP2 | 0.82 | 0.056 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| NUMBL | CRTC3 | 0.649 | 0.128 | hein_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
Related Complexes