hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01505.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
TIMP2 | Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) | 5 | UniProt   NCBI |
WNT10A | Protein Wnt-10a | 5 | UniProt   NCBI |
MMP2 | 72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX] | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  KEGG:05205 | 0.00267768543767 | 1.0 | WNT10A MMP2 | Proteoglycans in cancer |
  WP:WP4239 | 0.00368005765986 | 1.0 | WNT10A MMP2 | Epithelial to mesenchymal transition in colorectal cancer |
  KEGG:05200 | 0.0161326036311 | 1.0 | WNT10A MMP2 | Pathways in cancer |
  WP:WP5097 | 0.0186595012434 | 0.5 | MMP2 | CCL18 signaling pathway |
  CORUM:2798 | 0.0249718442457 | 0.5 | MMP2 | MMP-2-CLDN1 complex |
  WP:WP5087 | 0.0293715080819 | 1.0 | WNT10A MMP2 | Pleural mesothelioma |
  HP:0000684 | 0.0346981161387 | 1.0 | WNT10A MMP2 | Delayed eruption of teeth |
  HP:0006012 | 0.0499436884913 | 0.5 | MMP2 | Widened metacarpal shaft |
  HP:0008078 | 0.0499436884913 | 0.5 | MMP2 | Thin metatarsal cortices |
  HP:0008090 | 0.0499436884913 | 0.5 | MMP2 | Ankylosis of feet small joints |
  HP:0008133 | 0.0499436884913 | 0.5 | MMP2 | Distal tapering of metatarsals |
  HP:0011313 | 0.0499436884913 | 0.5 | WNT10A | Narrow nail |
  HP:0031405 | 0.0499436884913 | 0.5 | WNT10A | Poroma |
  HP:0031454 | 0.0499436884913 | 0.5 | WNT10A | Apocrine hidrocystoma |
  HP:0034946 | 0.0499436884913 | 0.5 | WNT10A | Multiple eyelid margin cysts |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 TIMP2 |  MMP2 | 0.971 | 0.248           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 WNT10A |  TIMP2 | 0.959 |            | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
Related Complexes