hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01609.1
Complex Portal: CPX-25253
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| STOML2 | Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7) | 5 | UniProt NCBI |
| GPRC5A | Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1) | 5 | UniProt NCBI |
| CYBRD1 | Plasma membrane ascorbate-dependent reductase CYBRD1 (EC 7.2.1.3) (Cytochrome b reductase 1) (Duodenal cytochrome b) (Ferric-chelate reductase 3) | 5 | UniProt NCBI |
| ABCG2 | Broad substrate specificity ATP-binding cassette transporter ABCG2 (EC 7.6.2.2) (ATP-binding cassette sub-family G member 2) (Breast cancer resistance protein) (CDw338) (Mitoxantrone resistance-associated protein) (Placenta-specific ATP-binding cassette transporter) (Urate exporter) (CD antigen CD338) | 5 | UniProt NCBI |
| ATP6V0A1 | V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) | 5 | UniProt NCBI |
| SLC34A2 | Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi3b) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-382551 | 6.77703888853e-05 | 0.833333333333 | STOML2 SLC34A2 CYBRD1 ATP6V0A1 ABCG2 | Transport of small molecules |
| REAC:R-HSA-917937 | 0.000155019643237 | 0.5 | ATP6V0A1 CYBRD1 ABCG2 | Iron uptake and transport |
| KEGG:04978 | 0.00779476406064 | 0.333333333333 | SLC34A2 CYBRD1 | Mineral absorption |
| GO:0031526 | 0.00860399003151 | 0.5 | SLC34A2 CYBRD1 ABCG2 | brush border membrane |
| HPA:0641502 | 0.0182368818217 | 0.333333333333 | SLC34A2 ABCG2 | endometrium; ciliated epithelial cells[>=Medium] |
| HPA:0641501 | 0.0268062509233 | 0.333333333333 | SLC34A2 ABCG2 | endometrium; ciliated epithelial cells[>=Low] |
| GO:0005903 | 0.0289892662643 | 0.5 | SLC34A2 CYBRD1 ABCG2 | brush border |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SLC34A2 | CYBRD1 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ABCG2 | ATP6V0A1 | 0.99 | 0.092 | hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CYBRD1 | GPRC5A | 0.986 | 0.108 | hein_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CYBRD1 | STOML2 | 0.979 | 0.084 | hein_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GPRC5A | ATP6V0A1 | 0.972 | 0.056 | hein_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| SLC34A2 | ATP6V0A1 | 0.97 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| STOML2 | ATP6V0A1 | 0.958 | 0.072 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| CYBRD1 | ATP6V0A1 | 0.957 | 0.132 | hein_WMM bioplex3_WMM WMM_only | |
| STOML2 | ABCG2 | 0.91 | 0.032 | hein_WMM bioplex3_HEK293 bioplex3_WMM WMM_only | |
| GPRC5A | ABCG2 | 0.827 | 0.212 | hein_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SLC34A2 | GPRC5A | 0.781 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CYBRD1 | ABCG2 | 0.773 | 0.07 | hein_WMM WMM_only | |
| STOML2 | GPRC5A | 0.498 | 0.07 | hein_WMM bioplex3_WMM gupta_WMM WMM_only | |
| SLC34A2 | STOML2 | 0.009 | bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
Related Complexes