hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01610.1
Complex Portal: CPX-15652
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FBLN5 | Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50) | 5 | UniProt NCBI |
| LTBP4 | Latent-transforming growth factor beta-binding protein 4 (LTBP-4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0012619 | 2.05051410255e-05 | 1.0 | FBLN5 LTBP4 | Multiple bladder diverticula |
| REAC:R-HSA-2129379 | 0.000693757271364 | 1.0 | FBLN5 LTBP4 | Molecules associated with elastic fibres |
| REAC:R-HSA-1566948 | 0.00107651990384 | 1.0 | FBLN5 LTBP4 | Elastic fibre formation |
| HP:0000015 | 0.00180445241025 | 1.0 | FBLN5 LTBP4 | Bladder diverticulum |
| HP:0004969 | 0.00240251902349 | 1.0 | FBLN5 LTBP4 | Peripheral pulmonary artery stenosis |
| HP:0002097 | 0.00470934738887 | 1.0 | FBLN5 LTBP4 | Emphysema |
| HP:0025487 | 0.0077851185427 | 1.0 | FBLN5 LTBP4 | Abnormal bladder morphology |
| HP:0004415 | 0.00849254590808 | 1.0 | FBLN5 LTBP4 | Pulmonary artery stenosis |
| GO:0048251 | 0.00983221512175 | 1.0 | FBLN5 LTBP4 | elastic fiber assembly |
| HP:0001582 | 0.0113495955576 | 1.0 | FBLN5 LTBP4 | Redundant skin |
| HP:0000776 | 0.0113495955576 | 1.0 | FBLN5 LTBP4 | Congenital diaphragmatic hernia |
| HP:0002021 | 0.0143057533888 | 1.0 | FBLN5 LTBP4 | Pyloric stenosis |
| HP:0004400 | 0.0152592424465 | 1.0 | FBLN5 LTBP4 | Abnormality of the pylorus |
| HP:0000775 | 0.0172584936965 | 1.0 | FBLN5 LTBP4 | Abnormality of the diaphragm |
| HP:0006532 | 0.0186596783332 | 1.0 | FBLN5 LTBP4 | Recurrent pneumonia |
| HP:0030966 | 0.0212433261025 | 1.0 | FBLN5 LTBP4 | Abnormal pulmonary artery morphology |
| HP:0000973 | 0.0227948817734 | 1.0 | FBLN5 LTBP4 | Cutis laxa |
| HP:0004414 | 0.0248112206409 | 1.0 | FBLN5 LTBP4 | Abnormality of the pulmonary artery |
| HP:0000239 | 0.0342128278011 | 1.0 | FBLN5 LTBP4 | Large fontanelles |
| HP:0007495 | 0.0397389633075 | 1.0 | FBLN5 LTBP4 | Prematurely aged appearance |
| HP:0008067 | 0.0434708989742 | 1.0 | FBLN5 LTBP4 | Abnormally lax or hyperextensible skin |
| REAC:R-HSA-1474244 | 0.0442193366216 | 1.0 | FBLN5 LTBP4 | Extracellular matrix organization |
| HP:0025426 | 0.0451215628267 | 1.0 | FBLN5 LTBP4 | Abnormal bronchus morphology |
| HP:0011328 | 0.0479410197177 | 1.0 | FBLN5 LTBP4 | Abnormality of fontanelles |
| CORUM:6914 | 0.0499419797295 | 0.5 | FBLN5 | ELN-FBLN5-FBN1 complex |
| HP:0025193 | 0.0499436884913 | 0.5 | LTBP4 | Posterolateral diaphragmatic hernia |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FBLN5 | LTBP4 | 0.97 | 0.152 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes