hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01617.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| STXBP5L | Syntaxin-binding protein 5-like (Lethal(2) giant larvae protein homolog 4) (Tomosyn-2) | 5 | UniProt NCBI |
| STX19 | Syntaxin-19 | 5 | UniProt NCBI |
| STXBP2 | Syntaxin-binding protein 2 (Protein unc-18 homolog 2) (Unc18-2) (Protein unc-18 homolog B) (Unc-18B) | 5 | UniProt NCBI |
| STXBP1 | Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000149 | 5.32774205779e-05 | 1.0 | STXBP1 STX19 STXBP5L STXBP2 | SNARE binding |
| GO:0006887 | 0.00273552953255 | 1.0 | STXBP1 STX19 STXBP5L STXBP2 | exocytosis |
| GO:0019905 | 0.00508133939815 | 0.75 | STXBP2 STXBP5L STXBP1 | syntaxin binding |
| GO:0048278 | 0.00951168180783 | 0.75 | STXBP1 STX19 STXBP2 | vesicle docking |
| GO:0140029 | 0.00951168180783 | 0.75 | STXBP1 STX19 STXBP2 | exocytic process |
| GO:0140056 | 0.0192043220783 | 0.75 | STXBP1 STX19 STXBP2 | organelle localization by membrane tethering |
| WP:WP481 | 0.0255965717397 | 0.5 | STXBP2 STXBP1 | Insulin signaling |
| GO:0022406 | 0.0280178993418 | 0.75 | STXBP1 STX19 STXBP2 | membrane docking |
| GO:0007269 | 0.0378152735667 | 0.75 | STXBP1 STX19 STXBP2 | neurotransmitter secretion |
| GO:0099643 | 0.0378152735667 | 0.75 | STXBP1 STX19 STXBP2 | signal release from synapse |
| GO:0032940 | 0.0497318663038 | 1.0 | STXBP1 STX19 STXBP5L STXBP2 | secretion by cell |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| STX19 | STXBP2 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| STX19 | STXBP1 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| STXBP5L | STX19 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| STXBP2 | STXBP1 | 0.983 | 0.02 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only treiber_WMM |
| STXBP5L | STXBP2 | 0.215 | bioplex_WMM bioplex3_WMM WMM_only | |
| STXBP5L | STXBP1 | 0.17 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes