hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01625.1
Complex Portal: CPX-16771
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BHMT2 | S-methylmethionine--homocysteine S-methyltransferase BHMT2 (SMM-hcy methyltransferase) (EC 2.1.1.10) (Betaine--homocysteine S-methyltransferase 2) | 5 | UniProt NCBI |
| BHMT | Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00270 | 0.00016825963378 | 1.0 | BHMT2 BHMT | Cysteine and methionine metabolism |
| WP:WP3940 | 0.000384350227487 | 1.0 | BHMT2 BHMT | One carbon metabolism and related pathways |
| REAC:R-HSA-1614635 | 0.000432316723289 | 1.0 | BHMT2 BHMT | Sulfur amino acid metabolism |
| WP:WP2525 | 0.000632070972113 | 1.0 | BHMT2 BHMT | Trans sulfuration one carbon metabolism and related pathways |
| GO:0008172 | 0.00468200720083 | 1.0 | BHMT2 BHMT | S-methyltransferase activity |
| GO:0043102 | 0.00983221512175 | 1.0 | BHMT2 BHMT | amino acid salvage |
| GO:0071265 | 0.00983221512175 | 1.0 | BHMT2 BHMT | L-methionine biosynthetic process |
| GO:0071267 | 0.00983221512175 | 1.0 | BHMT2 BHMT | L-methionine salvage |
| GO:0009086 | 0.016855225923 | 1.0 | BHMT2 BHMT | methionine biosynthetic process |
| HPA:0271143 | 0.019796826334 | 1.0 | BHMT2 BHMT | kidney; proximal tubules (cell body)[High] |
| GO:0006555 | 0.0309012475255 | 1.0 | BHMT2 BHMT | methionine metabolic process |
| GO:0000097 | 0.0365196561665 | 1.0 | BHMT2 BHMT | sulfur amino acid biosynthetic process |
| GO:0009067 | 0.0491610756088 | 1.0 | BHMT2 BHMT | aspartate family amino acid biosynthetic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BHMT2 | BHMT | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| BHMT2 | huMAP3_01625.1 huMAP3_04491.1 huMAP3_06947.1 huMAP3_09932.1 |
| BHMT | huMAP3_01625.1 huMAP3_09932.1 |