hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01626.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CYP3A5 | Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (Cytochrome P450-PCN3) | 5 | UniProt NCBI |
| CYP3A4 | Cytochrome P450 3A4 (EC 1.14.14.1) (1,4-cineole 2-exo-monooxygenase) (1,8-cineole 2-exo-monooxygenase) (EC 1.14.14.56) (Albendazole monooxygenase (sulfoxide-forming)) (EC 1.14.14.73) (Albendazole sulfoxidase) (CYPIIIA3) (CYPIIIA4) (Cholesterol 25-hydroxylase) (Cytochrome P450 3A3) (Cytochrome P450 HLp) (Cytochrome P450 NF-25) (Cytochrome P450-PCN1) (Nifedipine oxidase) (Quinine 3-monooxygenase) (EC 1.14.14.55) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2536 | 0.00454335014825 | 1.0 | CYP3A4 | Colchicine metabolic pathway |
| WP:WP2646 | 0.00908670029654 | 1.0 | CYP3A4 | Lidocaine metabolism |
| WP:WP2816 | 0.00908670029654 | 1.0 | CYP3A4 | Felbamate metabolism |
| WP:WP4174 | 0.00908670029654 | 1.0 | CYP3A4 | Metabolism of tetrahydrocannabinol THC |
| WP:WP2826 | 0.0181734005931 | 1.0 | CYP3A4 | Cocaine metabolism |
| WP:WP699 | 0.0318034510379 | 1.0 | CYP3A4 | Aflatoxin B1 metabolism |
| KEGG:00591 | 0.0353357458011 | 1.0 | CYP3A4 | Linoleic acid metabolism |
| WP:WP2874 | 0.0363468011862 | 1.0 | CYP3A4 | Liver X receptor pathway |
| WP:WP696 | 0.0363468011862 | 1.0 | CYP3A4 | Benzo a pyrene metabolism |
| WP:WP1604 | 0.0454335014827 | 1.0 | CYP3A4 | Codeine and morphine metabolism |
| WP:WP2879 | 0.0454335014827 | 1.0 | CYP3A4 | Farnesoid X receptor pathway |
| WP:WP5280 | 0.0454335014827 | 1.0 | CYP3A4 | Glucocorticoid biosynthesis |
| WP:WP229 | 0.049976851631 | 1.0 | CYP3A4 | Irinotecan pathway |
| WP:WP5324 | 0.049976851631 | 1.0 | CYP3A4 | Octadecanoid formation from linoleic acid |
| WP:WP697 | 0.049976851631 | 1.0 | CYP3A4 | Estrogen metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CYP3A5 | CYP3A4 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| CYP3A5 | huMAP3_01626.1 huMAP3_04464.1 huMAP3_14556.1 huMAP3_14585.1 huMAP3_14966.1 |
| CYP3A4 | huMAP3_01626.1 huMAP3_04464.1 huMAP3_14556.1 huMAP3_14585.1 huMAP3_14966.1 |