hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01637.1
Complex Portal: CPX-25538
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GTF3C5 | General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon) | 5 | UniProt NCBI |
| GTF3C2 | General transcription factor 3C polypeptide 2 (TF3C-beta) (Transcription factor IIIC 110 kDa subunit) (TFIIIC 110 kDa subunit) (TFIIIC110) (Transcription factor IIIC subunit beta) | 5 | UniProt NCBI |
| GTF3C3 | General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma) | 5 | UniProt NCBI |
| GTF3C1 | General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) | 5 | UniProt NCBI |
| PNMA2 | Paraneoplastic antigen Ma2 (40 kDa neuronal protein) (Onconeuronal antigen Ma2) (Paraneoplastic neuronal antigen MM2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1105 | 1.91772524101e-12 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | transcription factor IIIC multisubunit complex |
| CORUM:1101 | 1.91772524101e-12 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | transcription factor IIIC multisubunit complex |
| CORUM:1113 | 1.91772524101e-12 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | 5S-DNA-TFIIIA-TFIIIC2 subcomplex |
| CORUM:1106 | 5.7528607006e-12 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | TFIIIC containing-TOP1-SUB1 complex |
| CORUM:1114 | 1.34226065824e-11 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | 5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex |
| GO:0000127 | 1.97323122031e-09 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | transcription factor TFIIIC complex |
| GO:0042791 | 1.97323122031e-09 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | 5S class rRNA transcription by RNA polymerase III |
| REAC:R-HSA-76066 | 6.37824653444e-09 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| REAC:R-HSA-76061 | 6.37824653444e-09 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | RNA Polymerase III Transcription Initiation From Type 1 Promoter |
| GO:0090576 | 9.20740386965e-09 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | RNA polymerase III transcription regulator complex |
| REAC:R-HSA-76046 | 1.97771129067e-08 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | RNA Polymerase III Transcription Initiation |
| GO:0042797 | 2.76191861336e-08 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | tRNA transcription by RNA polymerase III |
| REAC:R-HSA-749476 | 3.50664405889e-08 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | RNA Polymerase III Abortive And Retractive Initiation |
| REAC:R-HSA-74158 | 3.50664405889e-08 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | RNA Polymerase III Transcription |
| GO:0009304 | 4.33992010508e-08 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | tRNA transcription |
| GO:0000995 | 6.50952358374e-08 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | RNA polymerase III general transcription initiation factor activity |
| GO:0009303 | 3.12047922974e-06 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | rRNA transcription |
| GO:0006383 | 2.55378856908e-05 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | transcription by RNA polymerase III |
| GO:0140223 | 2.55378856908e-05 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | general transcription initiation factor activity |
| GO:0098781 | 0.000625424261446 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | ncRNA transcription |
| GO:0006399 | 0.00526877477961 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | tRNA metabolic process |
| GO:0016072 | 0.00825090824596 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | rRNA metabolic process |
| REAC:R-HSA-74160 | 0.046583533294 | 0.8 | GTF3C5 GTF3C1 GTF3C3 GTF3C2 | Gene expression (Transcription) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GTF3C5 | GTF3C3 | 1.0 | 0.97 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () Malo gupta_WMM fraction boldt_WMM | |
| GTF3C1 | GTF3C3 | 1.0 | 0.866 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () Malo gupta_WMM fraction boldt_WMM | |
| GTF3C5 | GTF3C1 | 1.0 | 0.684 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM | |
| GTF3C3 | GTF3C2 | 1.0 | 0.522 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () boldt_WMM treiber_WMM | |
| GTF3C1 | GTF3C2 | 0.999 | 0.65 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () boldt_WMM | |
| GTF3C5 | GTF3C2 | 0.998 | 0.238 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () boldt_WMM | |
| PNMA2 | GTF3C3 | 0.994 | 0.09 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GTF3C1 | PNMA2 | 0.993 | 0.088 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GTF3C5 | PNMA2 | 0.964 | 0.13 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PNMA2 | GTF3C2 | 0.584 | 0.12 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes