hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01664.1
Complex Portal: CPX-10671
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAPK6 | Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) | 5 | UniProt NCBI |
| SERPINA1 | Alpha-1-antitrypsin (Alpha-1 protease inhibitor) (Alpha-1-antiproteinase) (Serpin A1) [Cleaved into: Short peptide from AAT (SPAAT)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5388 | 0.0499419797295 | 0.5 | SERPINA1 | SERPINA1-ELA2 complex |
| CORUM:5391 | 0.0499419797295 | 0.5 | SERPINA1 | SERPINA1-CTSG complex |
| HP:0032025 | 0.0499436884913 | 0.5 | SERPINA1 | Reduced serum alpha-1-antitrypsin |
| HP:0032967 | 0.0499436884913 | 0.5 | SERPINA1 | Panacinar emphysema |
| HP:0033709 | 0.0499436884913 | 0.5 | SERPINA1 | Increased sputum production |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MAPK6 | SERPINA1 | 0.959 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes