hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01665.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZC3H11A | Zinc finger CCCH domain-containing protein 11A | 5 | UniProt NCBI |
| DDX39A | ATP-dependent RNA helicase DDX39A (EC 3.6.4.13) (DEAD box protein 39) (Nuclear RNA helicase URH49) | 5 | UniProt NCBI |
| THOC2 | THO complex subunit 2 (Tho2) (hTREX120) | 5 | UniProt NCBI |
| DDX39B | Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein UAP56) (HLA-B-associated transcript 1 protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-72187 | 3.27520232439e-08 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | mRNA 3'-end processing |
| REAC:R-HSA-73856 | 5.72026034674e-08 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | RNA Polymerase II Transcription Termination |
| REAC:R-HSA-159236 | 8.80508022231e-08 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-72202 | 1.44287424832e-07 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | Transport of Mature Transcript to Cytoplasm |
| GO:0006406 | 1.89640394209e-05 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | mRNA export from nucleus |
| REAC:R-HSA-72203 | 2.20624569728e-05 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0051028 | 2.70701716559e-05 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | mRNA transport |
| GO:0006405 | 5.32774205779e-05 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | RNA export from nucleus |
| GO:0000346 | 6.34131776058e-05 | 0.75 | ZC3H11A DDX39B THOC2 | transcription export complex |
| CORUM:770 | 0.000107602882996 | 0.5 | THOC2 DDX39B | TREX complex |
| GO:0050658 | 0.000135789226712 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | RNA transport |
| GO:0050657 | 0.000135789226712 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | nucleic acid transport |
| GO:0051236 | 0.000151907686653 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | establishment of RNA localization |
| GO:0006403 | 0.000403362503007 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | RNA localization |
| GO:0051168 | 0.000427172539681 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | nuclear export |
| GO:0015931 | 0.000518885109813 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | nucleobase-containing compound transport |
| REAC:R-HSA-8953854 | 0.000868181971164 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | Metabolism of RNA |
| GO:0051169 | 0.00366770658506 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | nuclear transport |
| GO:0006913 | 0.00366770658506 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | nucleocytoplasmic transport |
| REAC:R-HSA-73857 | 0.00681752083972 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | RNA Polymerase II Transcription |
| REAC:R-HSA-74160 | 0.0112707156575 | 1.0 | ZC3H11A DDX39B DDX39A THOC2 | Gene expression (Transcription) |
| KEGG:03013 | 0.0125523722118 | 0.5 | THOC2 DDX39B | Nucleocytoplasmic transport |
| KEGG:03040 | 0.0192212154966 | 0.5 | THOC2 DDX39B | Spliceosome |
| CORUM:351 | 0.047170241778 | 0.5 | THOC2 DDX39B | Spliceosome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| THOC2 | DDX39B | 0.999 | 0.458 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| ZC3H11A | THOC2 | 0.998 | 0.486 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| DDX39A | DDX39B | 0.998 | 0.446 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM |
| ZC3H11A | DDX39A | 0.996 | 0.184 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| ZC3H11A | DDX39B | 0.996 | 0.308 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| DDX39A | THOC2 | 0.989 | 0.174 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM fraction treiber_WMM |
Related Complexes