hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01706.1
Complex Portal: CPX-5741
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PHB1 | Prohibitin 1 | 5 | UniProt NCBI |
| PHB2 | Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6289 | 1.70876175213e-05 | 1.0 | PHB1 PHB2 | prohibitin 2 complex, mitochondrial |
| WP:WP5038 | 0.000172808629413 | 1.0 | PHB1 PHB2 | Mitochondrial immune response to SARS CoV 2 |
| REAC:R-HSA-8949664 | 0.000205051410255 | 1.0 | PHB1 PHB2 | Processing of SMDT1 |
| REAC:R-HSA-8949215 | 0.000394723964742 | 1.0 | PHB1 PHB2 | Mitochondrial calcium ion transport |
| GO:0035632 | 0.000468200720083 | 1.0 | PHB1 PHB2 | mitochondrial prohibitin complex |
| GO:1990051 | 0.0028092043205 | 1.0 | PHB1 PHB2 | activation of protein kinase C activity |
| GO:0023035 | 0.0257510396046 | 1.0 | PHB1 PHB2 | CD40 signaling pathway |
| GO:0007202 | 0.0491610756088 | 1.0 | PHB1 PHB2 | activation of phospholipase C activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PHB1 | PHB2 | 1.0 | 0.974 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| PHB1 | huMAP3_01706.1 huMAP3_09671.1 huMAP3_10725.1 huMAP3_11743.1 |
| PHB2 | huMAP3_01706.1 huMAP3_09122.1 huMAP3_09671.1 huMAP3_10725.1 huMAP3_11743.1 huMAP3_12056.1 |