hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01717.1
Complex Portal: CPX-15067
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HEG1 | Protein HEG homolog 1 | 5 | UniProt NCBI |
| NECTIN1 | Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111) | 5 | UniProt NCBI |
| ITGA1 | Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a) | 5 | UniProt NCBI |
| CD276 | CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276) | 5 | UniProt NCBI |
| ENPP4 | Bis(5'-adenosyl)-triphosphatase ENPP4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) | 5 | UniProt NCBI |
| LGALS8 | Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1) | 5 | UniProt NCBI |
| KIAA0319L | Dyslexia-associated protein KIAA0319-like protein (Adeno-associated virus receptor) (AAVR) | 5 | UniProt NCBI |
| PTPRG | Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04520 | 0.0367995848147 | 0.285714285714 | NECTIN1 HEG1 | Adherens junction |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HEG1 | LGALS8 | 0.999 | 0.048 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LGALS8 | CD276 | 0.997 | 0.018 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LGALS8 | PTPRG | 0.997 | 0.048 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LGALS8 | KIAA0319L | 0.996 | 0.044 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ITGA1 | LGALS8 | 0.994 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NECTIN1 | LGALS8 | 0.991 | 0.054 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CD276 | KIAA0319L | 0.985 | 0.062 | bioplex_WMM bioplex3_WMM WMM_only | |
| ENPP4 | LGALS8 | 0.983 | 0.046 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| HEG1 | ITGA1 | 0.967 | 0.074 | bioplex_WMM bioplex3_WMM WMM_only | |
| NECTIN1 | ITGA1 | 0.955 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only | |
| HEG1 | NECTIN1 | 0.954 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only | |
| ITGA1 | KIAA0319L | 0.944 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only | |
| HEG1 | KIAA0319L | 0.933 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only | |
| NECTIN1 | PTPRG | 0.932 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only | |
| ITGA1 | CD276 | 0.931 | 0.122 | bioplex_WMM bioplex3_WMM WMM_only | |
| PTPRG | KIAA0319L | 0.929 | 0.096 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| ITGA1 | PTPRG | 0.899 | 0.156 | bioplex_WMM bioplex3_WMM WMM_only | |
| HEG1 | PTPRG | 0.895 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only | |
| NECTIN1 | CD276 | 0.845 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only | |
| NECTIN1 | KIAA0319L | 0.838 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only | |
| ENPP4 | ITGA1 | 0.791 | 0.078 |
mutually_exclusive (P17931)
|
bioplex_WMM bioplex3_WMM WMM_only |
| HEG1 | CD276 | 0.783 | 0.032 | bioplex_WMM bioplex3_WMM WMM_only | |
| ENPP4 | KIAA0319L | 0.767 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only | |
| PTPRG | CD276 | 0.68 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only | |
| ENPP4 | CD276 | 0.632 | 0.048 | bioplex_WMM bioplex3_WMM WMM_only | |
| ENPP4 | PTPRG | 0.444 | 0.048 | bioplex_WMM bioplex3_WMM WMM_only | |
| ENPP4 | HEG1 | 0.42 | 0.072 | bioplex_WMM bioplex3_WMM WMM_only | |
| ENPP4 | NECTIN1 | 0.17 | 0.04 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes