hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01729.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NDUFB2 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (Complex I-AGGG) (CI-AGGG) (NADH-ubiquinone oxidoreductase AGGG subunit) | 4 | UniProt NCBI |
| FAM185A | Protein FAM185A | 2 | UniProt NCBI |
| NDUFV2 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (NDUFV2) (EC 7.1.1.2) (NADH-ubiquinone oxidoreductase 24 kDa subunit) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4324 | 0.00167805708824 | 0.666666666667 | NDUFB2 NDUFV2 | Mitochondrial complex I assembly model OXPHOS system |
| WP:WP623 | 0.00193308448658 | 0.666666666667 | NDUFB2 NDUFV2 | Oxidative phosphorylation |
| CORUM:178 | 0.00308025137677 | 0.666666666667 | NDUFB2 NDUFV2 | Respiratory chain complex I (holoenzyme), mitochondrial |
| KEGG:04723 | 0.00533101781525 | 0.666666666667 | NDUFB2 NDUFV2 | Retrograde endocannabinoid signaling |
| WP:WP111 | 0.00536035090333 | 0.666666666667 | NDUFB2 NDUFV2 | Electron transport chain OXPHOS system in mitochondria |
| KEGG:00190 | 0.0056035932516 | 0.666666666667 | NDUFB2 NDUFV2 | Oxidative phosphorylation |
| KEGG:04932 | 0.00727572841175 | 0.666666666667 | NDUFB2 NDUFV2 | Non-alcoholic fatty liver disease |
| WP:WP4396 | 0.0104876474497 | 0.666666666667 | NDUFB2 NDUFV2 | Nonalcoholic fatty liver disease |
| REAC:R-HSA-6799198 | 0.0108549519561 | 0.666666666667 | NDUFB2 NDUFV2 | Complex I biogenesis |
| KEGG:05415 | 0.0124702277162 | 0.666666666667 | NDUFB2 NDUFV2 | Diabetic cardiomyopathy |
| KEGG:05208 | 0.0153557884392 | 0.666666666667 | NDUFB2 NDUFV2 | Chemical carcinogenesis - reactive oxygen species |
| KEGG:04714 | 0.0158142547588 | 0.666666666667 | NDUFB2 NDUFV2 | Thermogenesis |
| KEGG:05012 | 0.0212975456297 | 0.666666666667 | NDUFB2 NDUFV2 | Parkinson disease |
| KEGG:05020 | 0.022564200016 | 0.666666666667 | NDUFB2 NDUFV2 | Prion disease |
| KEGG:05016 | 0.0275851821163 | 0.666666666667 | NDUFB2 NDUFV2 | Huntington disease |
| REAC:R-HSA-611105 | 0.0329299631783 | 0.666666666667 | NDUFB2 NDUFV2 | Respiratory electron transport |
| KEGG:05014 | 0.0393573532881 | 0.666666666667 | NDUFB2 NDUFV2 | Amyotrophic lateral sclerosis |
| KEGG:05010 | 0.0433146801558 | 0.666666666667 | NDUFB2 NDUFV2 | Alzheimer disease |
| REAC:R-HSA-163200 | 0.049233254294 | 0.666666666667 | NDUFB2 NDUFV2 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NDUFB2 | NDUFV2 | 0.979 | 0.828 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| FAM185A | NDUFV2 | 0.952 | 0.092 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| NDUFB2 | FAM185A | 0.87 | 0.136 | bioplex3_WMM WMM_only |
Related Complexes