hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01732.1
Complex Portal: CPX-22875
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ATP5PD | ATP synthase subunit d, mitochondrial (ATPase subunit d) (ATP synthase peripheral stalk subunit d) | 5 | UniProt NCBI |
| ZFYVE27 | Protrudin (Spastic paraplegia 33 protein) (Zinc finger FYVE domain-containing protein 27) | 5 | UniProt NCBI |
| ATP5PB | ATP synthase F(0) complex subunit B1, mitochondrial (ATP synthase peripheral stalk-membrane subunit b) (ATP synthase proton-transporting mitochondrial F(0) complex subunit B1) (ATP synthase subunit b) (ATPase subunit b) | 5 | UniProt NCBI |
| CERS2 | Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (SP260) (Sphingosine N-acyltransferase CERS2) (EC 2.3.1.24) (Tumor metastasis-suppressor gene 1 protein) (Very-long-chain ceramide synthase CERS2) (EC 2.3.1.297) | 5 | UniProt NCBI |
| SLC6A5 | Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) | 5 | UniProt NCBI |
| SLC43A3 | Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3) | 5 | UniProt NCBI |
| YIF1B | Protein YIF1B (YIP1-interacting factor homolog B) | 5 | UniProt NCBI |
| NTSR1 | Neurotensin receptor type 1 (NT-R-1) (NTR1) (High-affinity levocabastine-insensitive neurotensin receptor) (NTRH) | 5 | UniProt NCBI |
| MT-ATP6 | ATP synthase subunit a (F-ATPase protein 6) | 5 | UniProt NCBI |
| TMEM120A | Ion channel TACAN (Transmembrane protein 120A) (Transmembrane protein induced by tumor necrosis factor alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:563 | 0.00180015784734 | 0.222222222222 | MT-ATP6 ATP5PD | F1F0-ATP synthase, mitochondrial |
| REAC:R-HSA-163210 | 0.0121597301349 | 0.222222222222 | MT-ATP6 ATP5PD | Formation of ATP by chemiosmotic coupling |
| REAC:R-HSA-8949613 | 0.0344394959621 | 0.222222222222 | MT-ATP6 ATP5PD | Cristae formation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ATP5PD | ATP5PB | 1.0 | 0.93 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM |
| ATP5PB | MT-ATP6 | 1.0 | 0.826 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM |
| ATP5PB | CERS2 | 0.999 | 0.07 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM | |
| ZFYVE27 | ATP5PB | 0.999 | 0.09 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ATP5PD | CERS2 | 0.999 | 0.152 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| ATP5PB | SLC6A5 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ATP5PD | MT-ATP6 | 0.994 | 0.84 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
| MT-ATP6 | CERS2 | 0.991 | 0.054 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only | |
| ATP5PB | SLC43A3 | 0.99 | 0.126 | hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ATP5PD | ZFYVE27 | 0.989 | 0.136 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ATP5PB | NTSR1 | 0.984 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ATP5PD | SLC6A5 | 0.981 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ATP5PD | SLC43A3 | 0.981 | 0.092 | hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ATP5PB | YIF1B | 0.978 | 0.142 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| ATP5PB | TMEM120A | 0.971 | 0.166 | hein_WMM bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| CERS2 | YIF1B | 0.955 | 0.044 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| ATP5PD | TMEM120A | 0.937 | 0.06 | bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | |
| CERS2 | TMEM120A | 0.934 | 0.068 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only | |
| CERS2 | NTSR1 | 0.922 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ATP5PD | YIF1B | 0.913 | 0.106 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ZFYVE27 | CERS2 | 0.894 | 0.102 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| YIF1B | TMEM120A | 0.849 | 0.03 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| SLC43A3 | CERS2 | 0.842 | 0.026 | hein_WMM bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ATP5PD | NTSR1 | 0.817 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CERS2 | SLC6A5 | 0.79 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| SLC43A3 | TMEM120A | 0.756 | 0.064 | hein_WMM bioplex3_WMM WMM_only | |
| NTSR1 | TMEM120A | 0.619 | bioplex3_WMM WMM_only | ||
| YIF1B | NTSR1 | 0.61 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MT-ATP6 | TMEM120A | 0.592 | 0.08 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| MT-ATP6 | SLC6A5 | 0.524 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SLC43A3 | MT-ATP6 | 0.357 | 0.034 | bioplex3_WMM WMM_only | |
| SLC43A3 | NTSR1 | 0.298 | bioplex3_WMM WMM_only | ||
| MT-ATP6 | NTSR1 | 0.243 | bioplex3_WMM WMM_only | ||
| MT-ATP6 | YIF1B | 0.242 | 0.088 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| SLC43A3 | YIF1B | 0.199 | 0.032 | bioplex3_WMM WMM_only | |
| SLC6A5 | YIF1B | 0.107 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ZFYVE27 | TMEM120A | 0.102 | 0.116 | bioplex3_WMM WMM_only | |
| ZFYVE27 | MT-ATP6 | 0.076 | 0.102 | bioplex3_WMM WMM_only | |
| ZFYVE27 | YIF1B | 0.061 | 0.108 | bioplex3_WMM WMM_only | |
| ZFYVE27 | SLC43A3 | 0.042 | 0.07 | bioplex3_WMM WMM_only | |
| ZFYVE27 | NTSR1 | 0.026 | bioplex3_WMM WMM_only |
Related Complexes