hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01734.1
Complex Portal: CPX-11045
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GYG1 | Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186) | 5 | UniProt NCBI |
| GYS1 | Glycogen [starch] synthase, muscle (EC 2.4.1.11) (Glycogen synthase 1) | 5 | UniProt NCBI |
| GBE1 | 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) | 5 | UniProt NCBI |
| AMY2A | Pancreatic alpha-amylase (PA) (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00500 | 1.20150051346e-07 | 1.0 | GBE1 GYG1 AMY2A | Starch and sucrose metabolism |
| WP:WP5173 | 8.83096676097e-05 | 0.666666666667 | GBE1 GYG1 | Disorders of galactose metabolism |
| REAC:R-HSA-3229121 | 0.000620139908703 | 0.666666666667 | GBE1 GYG1 | Glycogen storage diseases |
| REAC:R-HSA-3322077 | 0.000620139908703 | 0.666666666667 | GBE1 GYG1 | Glycogen synthesis |
| WP:WP500 | 0.000753202688136 | 0.666666666667 | GBE1 GYG1 | Glycogen synthesis and degradation |
| REAC:R-HSA-8982491 | 0.00188000535098 | 0.666666666667 | GBE1 GYG1 | Glycogen metabolism |
| REAC:R-HSA-5663084 | 0.00296224002415 | 0.666666666667 | GBE1 GYG1 | Diseases of carbohydrate metabolism |
| KEGG:01100 | 0.0189521995452 | 1.0 | GBE1 GYG1 AMY2A | Metabolic pathways |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| AMY2A | GYG1 | 0.985 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| AMY2A | GYS1 | 0.98 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GYS1 | GBE1 | 0.978 | 0.098 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| GYG1 | GBE1 | 0.978 | 0.048 |
structurally_consistent (P13807)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| GYG1 | GYS1 | 0.962 | 0.044 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM WMM_only |
| AMY2A | GBE1 | 0.002 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes