hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01743.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
UTP4 | U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component) | 5 | UniProt   NCBI |
WDR75 | WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog) | 5 | UniProt   NCBI |
NOL11 | Nucleolar protein 11 | 4 | UniProt   NCBI |
WDR43 | WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog) | 5 | UniProt   NCBI |
CNRIP1 | CB1 cannabinoid receptor-interacting protein 1 (CRIP-1) | 5 | UniProt   NCBI |
UTP15 | U3 small nucleolar RNA-associated protein 15 homolog | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-6790901 | 9.91336940667e-10 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | rRNA modification in the nucleus and cytosol |
  REAC:R-HSA-6791226 | 2.92772386913e-07 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | Major pathway of rRNA processing in the nucleolus and cytosol |
  REAC:R-HSA-8868773 | 3.84570671913e-07 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | rRNA processing in the nucleus and cytosol |
  KEGG:03008 | 4.41358358689e-07 | 0.666666666667 | UTP15 UTP4 WDR75 WDR43 | Ribosome biogenesis in eukaryotes |
  REAC:R-HSA-72312 | 4.98044887604e-07 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | rRNA processing |
  GO:0042274 | 2.95050662072e-06 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | ribosomal small subunit biogenesis |
  GO:0045943 | 1.82440357496e-05 | 0.666666666667 | UTP15 WDR43 WDR75 NOL11 | positive regulation of transcription by RNA polymerase I |
  GO:0006364 | 5.29122465223e-05 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | rRNA processing |
  GO:0006356 | 5.33450584461e-05 | 0.666666666667 | UTP15 WDR43 WDR75 NOL11 | regulation of transcription by RNA polymerase I |
  GO:0016072 | 0.000132089122668 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | rRNA metabolic process |
  GO:0006360 | 0.000166466176189 | 0.666666666667 | UTP15 WDR43 WDR75 NOL11 | transcription by RNA polymerase I |
  GO:2000234 | 0.0002304395259 | 0.5 | WDR43 WDR75 UTP15 | positive regulation of rRNA processing |
  REAC:R-HSA-8953854 | 0.000234756919958 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | Metabolism of RNA |
  GO:0032040 | 0.000403034704454 | 0.666666666667 | UTP15 UTP4 WDR75 WDR43 | small-subunit processome |
  GO:0042254 | 0.000451004131294 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | ribosome biogenesis |
  GO:2000232 | 0.0010743908712 | 0.5 | WDR43 WDR75 UTP15 | regulation of rRNA processing |
  GO:0030684 | 0.00172616540497 | 0.666666666667 | UTP15 UTP4 WDR75 WDR43 | preribosome |
  GO:0034470 | 0.00228495154828 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | ncRNA processing |
  GO:0022613 | 0.00397227337428 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | ribonucleoprotein complex biogenesis |
  GO:0034660 | 0.0153805016953 | 0.833333333333 | UTP15 UTP4 WDR43 WDR75 NOL11 | ncRNA metabolic process |
  GO:0034455 | 0.0210651876021 | 0.333333333333 | UTP4 NOL11 | t-UTP complex |
  GO:0030490 | 0.0271028431288 | 0.5 | UTP4 NOL11 WDR43 | maturation of SSU-rRNA |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 UTP4 |  UTP15 | 1.0 | 0.99           | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     treiber_WMM     |
 UTP4 |  WDR75 | 1.0 | 0.93           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     treiber_WMM     |
 UTP4 |  WDR43 | 1.0 | 0.946           | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     fraction     treiber_WMM     |
 UTP4 |  NOL11 | 1.0 | 0.94           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     treiber_WMM     |
 NOL11 |  WDR43 | 0.996 | 0.95           | bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     treiber_WMM     WMM_only     |
 WDR43 |  UTP15 | 0.996 | 0.924           | bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     treiber_WMM     WMM_only     |
 WDR75 |  WDR43 | 0.994 | 0.91           | bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     treiber_WMM     WMM_only     |
 NOL11 |  UTP15 | 0.989 | 0.986           | bioplex_WMM     bioplex3_WMM     youn_WMM     Malo     gupta_WMM     fraction     treiber_WMM     |
 WDR75 |  NOL11 | 0.968 | 0.942           | bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only     treiber_WMM     |
 CNRIP1 |  UTP4 | 0.966 | 0.008           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 WDR75 |  UTP15 | 0.963 | 0.966           | bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only     treiber_WMM     |
Related Complexes
Genename | Complexes |
---|---|
UTP4 | huMAP3_01549.1 huMAP3_01743.1 huMAP3_11250.1 huMAP3_14264.1 huMAP3_14364.1 |
WDR75 | huMAP3_01743.1 huMAP3_14264.1 |
NOL11 | huMAP3_01743.1 huMAP3_14264.1 huMAP3_14364.1 |
WDR43 | huMAP3_01743.1 huMAP3_14264.1 |
CNRIP1 | huMAP3_01549.1 huMAP3_01743.1 huMAP3_11167.1 huMAP3_11250.1 huMAP3_15267.1 |
UTP15 | huMAP3_01743.1 huMAP3_14264.1 |