hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01746.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| WDR48 | WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80) | 5 | UniProt NCBI |
| WDR20 | WD repeat-containing protein 20 (Protein DMR) | 5 | UniProt NCBI |
| USP46 | Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6635 | 2.33868713081e-10 | 1.0 | WDR48 WDR20 USP46 | WDR20-USP46-UAF1 complex |
| CORUM:6637 | 3.41752350426e-06 | 0.666666666667 | WDR48 USP46 | USP46-UAF1 complex |
| CORUM:6634 | 1.02521027753e-05 | 0.666666666667 | WDR48 WDR20 | WDR20-USP12-UAF1 complex |
| GO:0035800 | 0.0140440992017 | 0.666666666667 | WDR48 WDR20 | deubiquitinase activator activity |
| CORUM:3176 | 0.0499402709677 | 0.333333333333 | WDR48 | USP1-UAF1 complex |
| CORUM:6636 | 0.0499402709677 | 0.333333333333 | WDR48 | USP12-UAF1 complex |
| CORUM:6638 | 0.0499402709677 | 0.333333333333 | WDR48 | USP1-UAF1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| WDR20 | WDR48 | 1.0 | 0.144 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 gupta_WMM boldt_WMM |
| WDR20 | USP46 | 1.0 | 0.232 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM |
| WDR48 | USP46 | 0.998 | 0.224 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM |
Related Complexes