hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01749.1
Complex Portal: CPX-15281
Confidence: Extremely High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DOC2A | Double C2-like domain-containing protein alpha (Doc2) (Doc2-alpha) | 5 | UniProt   NCBI |
| RPH3A | Rabphilin-3A (Exophilin-1) | 5 | UniProt   NCBI |
| DOC2B | Double C2-like domain-containing protein beta (Doc2-beta) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   GO:0061669 | 1.92240082153e-06 | 1.0 | RPH3A DOC2A DOC2B | spontaneous neurotransmitter secretion |
|   GO:0098814 | 1.15344049292e-05 | 1.0 | RPH3A DOC2A DOC2B | spontaneous synaptic transmission |
|   GO:0017158 | 0.000148024863258 | 1.0 | RPH3A DOC2A DOC2B | regulation of calcium ion-dependent exocytosis |
|   GO:0017156 | 0.000629105668845 | 1.0 | RPH3A DOC2A DOC2B | calcium-ion regulated exocytosis |
|   GO:0098850 | 0.00140460216025 | 0.666666666667 | RPH3A DOC2A | extrinsic component of synaptic vesicle membrane |
|   GO:1903305 | 0.00460463056777 | 1.0 | RPH3A DOC2A DOC2B | regulation of regulated secretory pathway |
|   GO:0007269 | 0.00949377645712 | 1.0 | RPH3A DOC2A DOC2B | neurotransmitter secretion |
|   GO:0099643 | 0.00949377645712 | 1.0 | RPH3A DOC2A DOC2B | signal release from synapse |
|   GO:0006836 | 0.019623483106 | 1.0 | RPH3A DOC2A DOC2B | neurotransmitter transport |
|   GO:0017157 | 0.030542143052 | 1.0 | RPH3A DOC2A DOC2B | regulation of exocytosis |
|   GO:0045055 | 0.0328130751425 | 1.0 | RPH3A DOC2A DOC2B | regulated exocytosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  DOC2A |  DOC2B | 0.999 |            |
structurally_consistent (dimer)        
|
bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  RPH3A |  DOC2B | 0.994 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  DOC2A |  RPH3A | 0.078 |            |          | bioplex3_WMM     WMM_only     |
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