hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01758.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TUBGCP6 | Gamma-tubulin complex component 6 (GCP-6) | 5 | UniProt NCBI |
| TXNDC12 | Thioredoxin domain-containing protein 12 (EC 1.8.4.2) (Endoplasmic reticulum resident protein 18) (ER protein 18) (ERp18) (Endoplasmic reticulum resident protein 19) (ER protein 19) (ERp19) (Thioredoxin-like protein p19) (hTLP19) | 5 | UniProt NCBI |
| TUBGCP5 | Gamma-tubulin complex component 5 (GCP-5) | 5 | UniProt NCBI |
| MZT2A | Mitotic-spindle organizing protein 2A (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000931 | 2.15253635486e-05 | 0.75 | TUBGCP6 TUBGCP5 MZT2A | gamma-tubulin ring complex |
| CORUM:6893 | 5.12488211613e-05 | 0.5 | TUBGCP6 TUBGCP5 | Gamma-tubulin complex |
| WP:WP4940 | 9.18788843787e-05 | 0.5 | TUBGCP6 TUBGCP5 | 15q11 2 copy number variation syndrome |
| REAC:R-HSA-380287 | 0.000106339832101 | 0.75 | TUBGCP6 TUBGCP5 MZT2A | Centrosome maturation |
| REAC:R-HSA-380270 | 0.000106339832101 | 0.75 | TUBGCP6 TUBGCP5 MZT2A | Recruitment of mitotic centrosome proteins and complexes |
| REAC:R-HSA-380320 | 0.000164113242291 | 0.75 | TUBGCP6 TUBGCP5 MZT2A | Recruitment of NuMA to mitotic centrosomes |
| GO:0000930 | 0.000261258639543 | 0.75 | TUBGCP6 TUBGCP5 MZT2A | gamma-tubulin complex |
| REAC:R-HSA-69275 | 0.00153910156762 | 0.75 | TUBGCP6 TUBGCP5 MZT2A | G2/M Transition |
| REAC:R-HSA-453274 | 0.00158858251537 | 0.75 | TUBGCP6 TUBGCP5 MZT2A | Mitotic G2-G2/M phases |
| REAC:R-HSA-68877 | 0.0016906924478 | 0.75 | TUBGCP6 TUBGCP5 MZT2A | Mitotic Prometaphase |
| WP:WP3998 | 0.00862655865142 | 0.5 | TUBGCP6 TUBGCP5 | Prader Willi and Angelman syndrome |
| REAC:R-HSA-68886 | 0.0131851712206 | 0.75 | TUBGCP6 TUBGCP5 MZT2A | M Phase |
| GO:0000923 | 0.0280843539964 | 0.5 | TUBGCP6 TUBGCP5 | equatorial microtubule organizing center |
| REAC:R-HSA-69278 | 0.0329329593357 | 0.75 | TUBGCP6 TUBGCP5 MZT2A | Cell Cycle, Mitotic |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TUBGCP6 | TUBGCP5 | 1.0 | 0.258 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| TUBGCP5 | MZT2A | 1.0 | 0.072 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| TUBGCP6 | MZT2A | 0.999 | 0.168 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| TXNDC12 | MZT2A | 0.983 | 0.06 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| TUBGCP6 | TXNDC12 | 0.98 | 0.074 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| TXNDC12 | TUBGCP5 | 0.963 | 0.082 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| TUBGCP6 | huMAP3_01758.1 huMAP3_09443.1 huMAP3_14882.1 |
| TXNDC12 | huMAP3_01758.1 huMAP3_03304.1 huMAP3_09443.1 huMAP3_11976.1 huMAP3_14882.1 huMAP3_14900.1 |
| TUBGCP5 | huMAP3_01758.1 huMAP3_09443.1 huMAP3_14882.1 |
| MZT2A | huMAP3_01758.1 huMAP3_09443.1 huMAP3_14882.1 |