hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01762.1
Complex Portal: CPX-20157
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CTSA | Lysosomal protective protein (EC 3.4.16.5) (Carboxypeptidase C) (Carboxypeptidase L) (Cathepsin A) (Protective protein cathepsin A) (PPCA) (Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain] | 5 | UniProt NCBI |
| GLB1 | Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) (Elastin receptor 1) | 5 | UniProt NCBI |
| KHK | Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5657562 | 0.0124859221228 | 1.0 | KHK | Essential fructosuria |
| WP:WP690 | 0.0181734005931 | 1.0 | KHK | Polyol pathway |
| REAC:R-HSA-70350 | 0.0499436884912 | 1.0 | KHK | Fructose catabolism |
| WP:WP5178 | 0.049976851631 | 1.0 | KHK | Disorders of fructose metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CTSA | GLB1 | 0.999 | 0.498 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | |
| GLB1 | KHK | 0.978 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| CTSA | KHK | 0.976 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| CTSA | huMAP3_01762.1 huMAP3_09469.1 huMAP3_12161.1 huMAP3_13217.1 |
| GLB1 | huMAP3_01762.1 huMAP3_09469.1 |
| KHK | huMAP3_01762.1 huMAP3_07983.1 huMAP3_09469.1 huMAP3_12161.1 huMAP3_13217.1 huMAP3_14177.1 |