hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01787.1
Complex Portal: CPX-21626
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ANKRD55 | Ankyrin repeat domain-containing protein 55 | 5 | UniProt NCBI |
| CDR2L | Cerebellar degeneration-related protein 2-like (Paraneoplastic 62 kDa antigen) | 5 | UniProt NCBI |
| YWHAQ | 14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1) | 5 | UniProt NCBI |
| DMTN | Dematin (Dematin actin-binding protein) (Erythrocyte membrane protein band 4.9) | 5 | UniProt NCBI |
| SFN | 14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin) | 5 | UniProt NCBI |
| A0A1X9RU27 | None | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9614399 | 1.55272913081e-06 | 0.5 | A0A1X9RU27 YWHAQ SFN | Regulation of localization of FOXO transcription factors |
| REAC:R-HSA-9614085 | 0.000239738718613 | 0.5 | A0A1X9RU27 YWHAQ SFN | FOXO-mediated transcription |
| REAC:R-HSA-9755779 | 0.00170100530318 | 0.333333333333 | SFN YWHAQ | SARS-CoV-2 targets host intracellular signalling and regulatory pathways |
| REAC:R-HSA-75035 | 0.00200991204249 | 0.333333333333 | SFN YWHAQ | Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex |
| REAC:R-HSA-111447 | 0.00270466310657 | 0.333333333333 | SFN YWHAQ | Activation of BAD and translocation to mitochondria |
| REAC:R-HSA-9735871 | 0.00270466310657 | 0.333333333333 | SFN YWHAQ | SARS-CoV-1 targets host intracellular signalling and regulatory pathways |
| WP:WP4542 | 0.00407076266464 | 0.333333333333 | A0A1X9RU27 YWHAQ | Leukocyte intrinsic Hippo pathway functions |
| REAC:R-HSA-114452 | 0.0111743831709 | 0.333333333333 | SFN YWHAQ | Activation of BH3-only proteins |
| REAC:R-HSA-109606 | 0.0339259639772 | 0.333333333333 | SFN YWHAQ | Intrinsic Pathway for Apoptosis |
| CORUM:6242 | 0.0499436884912 | 0.166666666667 | YWHAQ | 14-3-3q-SGK1-tau complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| YWHAQ | SFN | 0.997 | 0.51 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM treiber_WMM |
| ANKRD55 | YWHAQ | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| CDR2L | SFN | 0.99 | 0.544 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CDR2L | YWHAQ | 0.988 | 0.554933333333 | bioplex3_HEK293 bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM WMM_only | |
| YWHAQ | DMTN | 0.987 | 0.572 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| DMTN | SFN | 0.966 | 0.5104 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ANKRD55 | SFN | 0.128 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 | ||
| CDR2L | DMTN | 0.076 | 0.154 | bioplex3_WMM WMM_only |
Related Complexes