hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01794.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GABRA3 | Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3) | 5 | UniProt NCBI |
| GABRA5 | Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A) receptor subunit alpha-5) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05033 | 4.48692356747e-05 | 1.0 | GABRA3 GABRA5 | Nicotine addiction |
| WP:WP4159 | 0.000117475817039 | 1.0 | GABRA3 GABRA5 | GABA receptor signaling |
| KEGG:04742 | 0.000146800434109 | 1.0 | GABRA3 GABRA5 | Taste transduction |
| WP:WP4829 | 0.000172808629413 | 1.0 | GABRA3 GABRA5 | mBDNF and proBDNF regulation of GABA neurotransmission |
| KEGG:04727 | 0.000359441594481 | 1.0 | GABRA3 GABRA5 | GABAergic synapse |
| KEGG:05032 | 0.00037033376401 | 1.0 | GABRA3 GABRA5 | Morphine addiction |
| KEGG:04723 | 0.0011414018249 | 1.0 | GABRA3 GABRA5 | Retrograde endocannabinoid signaling |
| REAC:R-HSA-977443 | 0.00140118463675 | 1.0 | GABRA3 GABRA5 | GABA receptor activation |
| KEGG:04080 | 0.00282724955659 | 1.0 | GABRA3 GABRA5 | Neuroactive ligand-receptor interaction |
| GO:0008503 | 0.00983221512175 | 1.0 | GABRA3 GABRA5 | benzodiazepine receptor activity |
| GO:0022851 | 0.0131096201623 | 1.0 | GABRA3 GABRA5 | GABA-gated chloride ion channel activity |
| WP:WP5420 | 0.0144418640295 | 1.0 | GABRA3 GABRA5 | ADHD and autism ASD linked metabolic pathways and SNP |
| GO:0005237 | 0.016855225923 | 1.0 | GABRA3 GABRA5 | inhibitory extracellular ligand-gated monoatomic ion channel activity |
| GO:1902711 | 0.0210690324038 | 1.0 | GABRA3 GABRA5 | GABA-A receptor complex |
| GO:0004890 | 0.0210690324038 | 1.0 | GABRA3 GABRA5 | GABA-A receptor activity |
| REAC:R-HSA-112314 | 0.0211937720117 | 1.0 | GABRA3 GABRA5 | Neurotransmitter receptors and postsynaptic signal transmission |
| HP:0032792 | 0.0248112206409 | 1.0 | GABRA3 GABRA5 | Tonic seizure |
| GO:1902710 | 0.0309012475255 | 1.0 | GABRA3 GABRA5 | GABA receptor complex |
| GO:0099095 | 0.0309012475255 | 1.0 | GABRA3 GABRA5 | ligand-gated monoatomic anion channel activity |
| REAC:R-HSA-112315 | 0.0350347422039 | 1.0 | GABRA3 GABRA5 | Transmission across Chemical Synapses |
| GO:0016917 | 0.0365196561665 | 1.0 | GABRA3 GABRA5 | GABA receptor activity |
| GO:0007214 | 0.0426062655276 | 1.0 | GABRA3 GABRA5 | gamma-aminobutyric acid signaling pathway |
| HP:0032786 | 0.0499436884913 | 0.5 | GABRA5 | Migrating focal seizure |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GABRA3 | GABRA5 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| GABRA3 | huMAP3_01794.1 huMAP3_02000.1 huMAP3_08794.1 huMAP3_09136.1 huMAP3_10354.1 huMAP3_15126.1 |
| GABRA5 | huMAP3_01794.1 |