hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01817.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MLLT6 | Protein AF-17 (ALL1-fused gene from chromosome 17 protein) | 5 | UniProt NCBI |
| DOT1L | Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.360) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4) | 5 | UniProt NCBI |
| MLLT10 | Protein AF-10 (ALL1-fused gene from chromosome 10 protein) | 5 | UniProt NCBI |
| MLLT3 | Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05202 | 0.0295193078423 | 0.5 | DOT1L MLLT3 | Transcriptional misregulation in cancer |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MLLT6 | DOT1L | 1.0 | 0.134 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 |
| MLLT6 | MLLT10 | 0.999 | 0.122 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| DOT1L | MLLT10 | 0.999 | 0.128 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () |
| MLLT6 | MLLT3 | 0.997 | 0.3 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| DOT1L | MLLT3 | 0.995 | 0.144 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| MLLT10 | MLLT3 | 0.968 | 0.206 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes