List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_01845.1

Confidence: Extremely High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
BMF	Bcl-2-modifying factor	5	UniProt   NCBI
TNIP3	TNFAIP3-interacting protein 3 (A20-binding inhibitor of NF-kappa-B activation 3) (ABIN-3) (Listeria-induced gene protein)	5	UniProt   NCBI
BCL2L2	Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)	5	UniProt   NCBI
BID	BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]	5	UniProt   NCBI
BIK	Bcl-2-interacting killer (Apoptosis inducer NBK) (BIP1) (BP4)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP1772	2.64882854506e-05	0.75	BIK BMF BID	Apoptosis modulation and signaling
REAC:R-HSA-111453	0.000368856835097	0.5	BMF BID	BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
GO:0090200	0.000591522022343	0.75	BIK BMF BID	positive regulation of release of cytochrome c from mitochondria
WP:WP3611	0.0022974831852	0.5	BMF BID	Photodynamic therapy induced AP 1 survival signaling
GO:0090199	0.00274053853655	0.75	BIK BMF BID	regulation of release of cytochrome c from mitochondria
REAC:R-HSA-114452	0.00444848198459	0.5	BMF BID	Activation of BH3-only proteins
GO:0001836	0.00508133939815	0.75	BIK BMF BID	release of cytochrome c from mitochondria
GO:0010822	0.0131184183431	0.75	BIK BMF BID	positive regulation of mitochondrion organization
REAC:R-HSA-109606	0.0135329645116	0.5	BMF BID	Intrinsic Pathway for Apoptosis
GO:0008637	0.0291371139957	0.75	BIK BMF BID	apoptotic mitochondrial changes



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
TNIP3	BCL2L2	0.999		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116
BCL2L2	BIK	0.994		bioplex3_WMM     bioplex3_HCT116     WMM_only
BMF	BCL2L2	0.991		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
BCL2L2	BID	0.99		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116
TNIP3	BIK	0.616		bioplex3_WMM     WMM_only
BID	BIK	0.605		bioplex3_WMM     WMM_only
BMF	TNIP3	0.557		bioplex_WMM     bioplex3_WMM     WMM_only
BMF	BIK	0.214		bioplex3_WMM     WMM_only
TNIP3	BID	0.175		bioplex_WMM     bioplex3_WMM     WMM_only
BMF	BID	0.164		bioplex_WMM     bioplex3_WMM     WMM_only





Related Complexes

Genename	Complexes
BMF	huMAP3_01845.1 huMAP3_02510.1 huMAP3_08709.1 huMAP3_10845.1
TNIP3	huMAP3_01845.1 huMAP3_08709.1 huMAP3_10845.1 huMAP3_11267.1
BCL2L2	huMAP3_01845.1 huMAP3_02510.1 huMAP3_08709.1 huMAP3_10845.1
BID	huMAP3_01845.1 huMAP3_04404.1 huMAP3_14442.1
BIK	huMAP3_01845.1 huMAP3_08181.1 huMAP3_10695.1 huMAP3_11267.1