hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_01877.1
Complex Portal: CPX-13945
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DAG1 | Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)] | 5 | UniProt NCBI |
| MET | Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2541 | 0.0249718442457 | 0.5 | MET | HGF-Met complex |
| HP:0001832 | 0.0286559345832 | 1.0 | DAG1 MET | Abnormal metatarsal morphology |
| REAC:R-HSA-5083628 | 0.0499419797295 | 0.5 | DAG1 | Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 |
| REAC:R-HSA-9734091 | 0.0499419797295 | 0.5 | MET | Drug-mediated inhibition of MET activation |
| CORUM:422 | 0.0499419797295 | 0.5 | DAG1 | Beta-dystroglycan-caveolin-3 complex |
| CORUM:6798 | 0.0499419797295 | 0.5 | MET | S1PR1-c-Met-ITGB4 complex, HGF- or S1P-induced |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DAG1 | MET | 0.964 | 0.126 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| DAG1 | huMAP3_01877.1 |
| MET | huMAP3_01877.1 huMAP3_07785.1 |