hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01879.1
Complex Portal: CPX-17552
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TLK2 | Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2) | 5 | UniProt NCBI |
| TLK1 | Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1) | 5 | UniProt NCBI |
| SPATA1 | Spermatogenesis-associated protein 1 (Sperm-specific protein SP-2) | 3 | UniProt NCBI |
| CIZ1 | Cip1-interacting zinc finger protein (CDKN1A-interacting zinc finger protein 1) (Nuclear protein NP94) (Zinc finger protein 356) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP1530 | 0.00234933503753 | 0.666666666667 | TLK2 TLK1 | miRNA regulation of DNA damage response |
| WP:WP707 | 0.00234933503753 | 0.666666666667 | TLK2 TLK1 | DNA damage response |
| HP:0002883 | 0.00587635932745 | 0.666666666667 | TLK2 CIZ1 | Hyperventilation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TLK1 | TLK2 | 1.0 | 0.122 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM |
| SPATA1 | TLK2 | 0.991 | bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| TLK1 | SPATA1 | 0.991 | bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| CIZ1 | TLK2 | 0.967 | 0.15 | hein_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| TLK1 | CIZ1 | 0.895 | 0.068 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
Related Complexes