List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_01899.1

Confidence: Extremely High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
WDR7	WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)	3	UniProt   NCBI
NCOA7	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1)	5	UniProt   NCBI
DMXL1	DmX-like protein 1 (X-like 1 protein)	3	UniProt   NCBI
RAPGEF3	Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI)	5	UniProt   NCBI
TBC1D24	TBC1 domain family member 24	5	UniProt   NCBI
ROGDI	Protein rogdi homolog	5	UniProt   NCBI
ATP6V1B2	V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2)	5	UniProt   NCBI
ATP6V1E2	V-type proton ATPase subunit E 2 (V-ATPase subunit E 2) (Vacuolar proton pump subunit E 2)	4	UniProt   NCBI
ATP6V1B1	V-type proton ATPase subunit B, kidney isoform (V-ATPase subunit B 1) (Endomembrane proton pump 58 kDa subunit) (Vacuolar proton pump subunit B 1)	5	UniProt   NCBI
ATP6V1E1	V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)	5	UniProt   NCBI
ATP6V1C2	V-type proton ATPase subunit C 2 (V-ATPase subunit C 2) (Vacuolar proton pump subunit C 2)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:04966	4.89677977907e-08	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Collecting duct acid secretion
REAC:R-HSA-77387	5.42263887023e-07	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Insulin receptor recycling
REAC:R-HSA-917977	5.42263887023e-07	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Transferrin endocytosis and recycling
KEGG:05110	8.17994410312e-07	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Vibrio cholerae infection
REAC:R-HSA-1222556	8.32503276128e-07	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	ROS and RNS production in phagocytes
GO:0044769	1.81927560642e-06	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
GO:0046961	1.81927560642e-06	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	proton-transporting ATPase activity, rotational mechanism
KEGG:04721	2.66396544843e-06	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Synaptic vesicle cycle
GO:0042625	2.72801663605e-06	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	ATPase-coupled ion transmembrane transporter activity
KEGG:05120	3.2509227435e-06	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Epithelial cell signaling in Helicobacter pylori infection
KEGG:05323	4.4373016651e-06	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Rheumatoid arthritis
REAC:R-HSA-917937	7.11352916135e-06	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Iron uptake and transport
REAC:R-HSA-9639288	7.69169245208e-06	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Amino acids regulate mTORC1
REAC:R-HSA-74752	1.46096587181e-05	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Signaling by Insulin receptor
KEGG:00190	4.70127218921e-05	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Oxidative phosphorylation
KEGG:04145	6.44593178058e-05	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Phagosome
KEGG:04150	0.00010183820007	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	mTOR signaling pathway
REAC:R-HSA-983712	0.000240716590629	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Ion channel transport
GO:0019829	0.000361003342891	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	ATPase-coupled monoatomic cation transmembrane transporter activity
HP:0031423	0.000413118282426	0.2	TBC1D24 ATP6V1B2	Small cerebellar cortex
REAC:R-HSA-9711097	0.000557795386686	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Cellular response to starvation
HP:0031282	0.00123890251767	0.2	TBC1D24 ATP6V1B2	Malalignment of the great toenail
HP:0010347	0.00123890251767	0.2	TBC1D24 ATP6V1B2	Aplasia/Hypoplasia of the phalanges of the 2nd toe
HP:0010324	0.00123890251767	0.2	TBC1D24 ATP6V1B2	Abnormal morphology of phalanx of the 2nd toe
KEGG:05165	0.00154195382833	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Human papillomavirus infection
GO:0033180	0.0018977127037	0.3	ATP6V1B2 ATP6V1C2 ATP6V1E1	proton-transporting V-type ATPase, V1 domain
GO:0000221	0.0018977127037	0.3	ATP6V1B2 ATP6V1C2 ATP6V1E1	vacuolar proton-transporting V-type ATPase, V1 domain
HP:0011326	0.00247690070118	0.2	TBC1D24 ATP6V1B2	Anterior plagiocephaly
KEGG:04142	0.00336653177296	0.3	WDR7 DMXL1 NCOA7	Lysosome
HP:0031422	0.00412666115323	0.2	TBC1D24 ATP6V1B2	Abnormal cerebellar cortex morphology
GO:0042626	0.00495760415907	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	ATPase-coupled transmembrane transporter activity
GO:0033178	0.00780402634424	0.3	ATP6V1B2 ATP6V1C2 ATP6V1E1	proton-transporting two-sector ATPase complex, catalytic domain
HP:0006891	0.0148343034129	0.2	TBC1D24 ATP6V1E1	Thick cerebral cortex
HP:0100797	0.0148343034129	0.2	TBC1D24 ATP6V1B2	Toenail dysplasia
HP:0000675	0.0148343034129	0.2	TBC1D24 ATP6V1B2	Macrodontia of permanent maxillary central incisor
HP:0000121	0.01488128731	0.3	TBC1D24 ATP6V1E1 ATP6V1B2	Nephrocalcinosis
GO:0015078	0.0149986773182	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	proton transmembrane transporter activity
GO:0016471	0.0176420810956	0.3	ATP6V1B2 ATP6V1C2 ATP6V1E1	vacuolar proton-transporting V-type ATPase complex
HP:0010497	0.0185361113698	0.2	TBC1D24 ATP6V1B2	Sirenomelia
GO:0033176	0.0202810995064	0.3	ATP6V1B2 ATP6V1C2 ATP6V1E1	proton-transporting V-type ATPase complex
HP:0000200	0.0226469783291	0.2	TBC1D24 ATP6V1B2	Short lingual frenulum
HP:0010319	0.0226469783291	0.2	TBC1D24 ATP6V1B2	Abnormal second toe morphology
HP:0011081	0.0226469783291	0.2	TBC1D24 ATP6V1B2	Incisor macrodontia
HP:0012402	0.0226469783291	0.2	TBC1D24 ATP6V1B2	Increased urine alpha-ketoglutarate concentration
HP:0008110	0.0271664548802	0.2	TBC1D24 ATP6V1B2	Equinovarus deformity
HP:0000187	0.0320940919357	0.2	TBC1D24 ATP6V1B2	Broad alveolar ridges
HP:0011409	0.0320940919357	0.2	TBC1D24 ATP6V1B2	Abnormal placental membrane morphology
HP:0012401	0.0320940919357	0.2	TBC1D24 ATP6V1B2	Abnormal urine alpha-ketoglutarate concentration
REAC:R-HSA-9006934	0.0331471231971	0.4	ATP6V1B2 ATP6V1C2 ATP6V1E2 ATP6V1E1	Signaling by Receptor Tyrosine Kinases
HP:0004626	0.0431720528278	0.2	TBC1D24 ATP6V1B2	Lumbar scoliosis



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
ATP6V1E2	ATP6V1C2	1.0
ATP6V1B2	ATP6V1E1	1.0	0.93
ATP6V1E2	ATP6V1B1	1.0
WDR7	ROGDI	1.0
DMXL1	ROGDI	0.999	0.11
ATP6V1E1	ATP6V1C2	0.999
ATP6V1B1	ATP6V1E1	0.999
ATP6V1B2	ATP6V1B1	0.999
ATP6V1B2	ATP6V1E2	0.999
ATP6V1B2	ATP6V1C2	0.999
WDR7	ATP6V1B1	0.998
NCOA7	ATP6V1B1	0.998
DMXL1	ATP6V1B1	0.997
NCOA7	ATP6V1B2	0.996	0.074
TBC1D24	ATP6V1B2	0.994	0.078
DMXL1	ATP6V1B2	0.991	0.078
ATP6V1B2	ROGDI	0.989	0.124
ATP6V1B1	ATP6V1C2	0.988
TBC1D24	ATP6V1B1	0.987
ATP6V1B2	RAPGEF3	0.984	0.17
WDR7	ATP6V1B2	0.98
WDR7	DMXL1	0.978
ATP6V1E2	ATP6V1E1	0.978
DMXL1	ATP6V1C2	0.975
NCOA7	ATP6V1E2	0.969
WDR7	NCOA7	0.964
NCOA7	DMXL1	0.964	0.06
NCOA7	ATP6V1C2	0.964
DMXL1	ATP6V1E2	0.958
WDR7	ATP6V1E2	0.957
WDR7	ATP6V1C2	0.952
DMXL1	ATP6V1E1	0.946	0.044
NCOA7	ATP6V1E1	0.936	0.052
WDR7	ATP6V1E1	0.933
TBC1D24	WDR7	0.799
TBC1D24	DMXL1	0.799	0.022
TBC1D24	NCOA7	0.672	0.058
TBC1D24	ATP6V1E2	0.672
TBC1D24	ATP6V1E1	0.654	0.046
TBC1D24	ATP6V1C2	0.646
WDR7	RAPGEF3	0.415
DMXL1	RAPGEF3	0.415	0.082
ATP6V1E2	RAPGEF3	0.415
NCOA7	RAPGEF3	0.415	0.072
RAPGEF3	ROGDI	0.415	0.066
ATP6V1B1	RAPGEF3	0.415
ATP6V1B1	ROGDI	0.415
ATP6V1C2	RAPGEF3	0.278
ATP6V1E2	ROGDI	0.274
NCOA7	ROGDI	0.274	0.056
ATP6V1E1	RAPGEF3	0.254	0.06
ATP6V1E1	ROGDI	0.113	0.056
ATP6V1C2	ROGDI	0.113
TBC1D24	RAPGEF3	0.113	0.042
TBC1D24	ROGDI	0.076	0.11





Related Complexes

Genename	Complexes
WDR7	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_03469.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
NCOA7	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
DMXL1	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_03469.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
RAPGEF3	huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_12042.1 huMAP3_13872.1
TBC1D24	huMAP3_00552.1 huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13467.1 huMAP3_13872.1
ROGDI	huMAP3_01501.1 huMAP3_01899.1 huMAP3_03469.1 huMAP3_05952.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1B2	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1E2	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1B1	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1E1	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1C2	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_12827.1 huMAP3_13872.1