hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01909.1
Complex Portal: CPX-10329
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) | 5 | UniProt NCBI |
| PAFAH1B3 | Platelet-activating factor acetylhydrolase IB subunit alpha1 (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma) | 5 | UniProt NCBI |
| PAFAH1B2 | Platelet-activating factor acetylhydrolase IB subunit alpha2 (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5409 | 9.30193945901e-09 | 1.0 | PAFAH1B1 PAFAH1B2 PAFAH1B3 | PAFAH1B1 copy number variation |
| GO:0008247 | 9.61200410764e-08 | 1.0 | PAFAH1B1 PAFAH1B2 PAFAH1B3 | 1-alkyl-2-acetylglycerophosphocholine esterase complex |
| KEGG:00565 | 4.05898216937e-07 | 1.0 | PAFAH1B1 PAFAH1B2 PAFAH1B3 | Ether lipid metabolism |
| REAC:R-HSA-6811436 | 9.1454019665e-06 | 1.0 | PAFAH1B1 PAFAH1B2 PAFAH1B3 | COPI-independent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-8856688 | 0.000151878996944 | 1.0 | PAFAH1B1 PAFAH1B2 PAFAH1B3 | Golgi-to-ER retrograde transport |
| REAC:R-HSA-6811442 | 0.000550411351332 | 1.0 | PAFAH1B1 PAFAH1B2 PAFAH1B3 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0047179 | 0.00421361424067 | 0.666666666667 | PAFAH1B3 PAFAH1B2 | platelet-activating factor acetyltransferase activity |
| REAC:R-HSA-199991 | 0.0145539954891 | 1.0 | PAFAH1B1 PAFAH1B2 PAFAH1B3 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.017135828319 | 1.0 | PAFAH1B1 PAFAH1B2 PAFAH1B3 | Vesicle-mediated transport |
| KEGG:01100 | 0.0189521995452 | 1.0 | PAFAH1B1 PAFAH1B2 PAFAH1B3 | Metabolic pathways |
| GO:0003847 | 0.0210651876021 | 0.666666666667 | PAFAH1B3 PAFAH1B2 | 1-alkyl-2-acetylglycerophosphocholine esterase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PAFAH1B3 | PAFAH1B2 | 1.0 | 0.406 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 boldt_WMM |
| PAFAH1B1 | PAFAH1B3 | 0.999 | 0.048 |
structurally_consistent (P68402)
structurally_consistent (dimer) |
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 fraction boldt_WMM |
| PAFAH1B1 | PAFAH1B2 | 0.997 | 0.52 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 fraction boldt_WMM |
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