hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01913.1
Complex Portal: CPX-21226
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BZW1 | eIF5-mimic protein 2 (Basic leucine zipper and W2 domain-containing protein 1) (Protein Orf) | 5 | UniProt NCBI |
| TBRG4 | FAST kinase domain-containing protein 4 (Cell cycle progression restoration protein 2) (Cell cycle progression protein 2) (Protein TBRG4) (Transforming growth factor beta regulator 4) | 5 | UniProt NCBI |
| PRRT2 | Proline-rich transmembrane protein 2 (Dispanin subfamily B member 3) (DSPB3) | 5 | UniProt NCBI |
| PGAP3 | Post-GPI attachment to proteins factor 3 (COS16 homolog) (hCOS16) (Gene coamplified with ERBB2 protein) (PER1-like domain-containing protein 1) | 5 | UniProt NCBI |
| FRRS1L | DOMON domain-containing protein FRRS1L (Brain protein CG-6) (Ferric-chelate reductase 1-like protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0011198 | 0.0267599042538 | 0.6 | PRRT2 FRRS1L PGAP3 | EEG with generalized epileptiform discharges |
| HP:0002487 | 0.0297055420477 | 0.4 | PRRT2 FRRS1L | Hyperkinetic movements |
| HP:0002266 | 0.0358235710582 | 0.4 | PRRT2 FRRS1L | Focal clonic seizure |
| HP:0011182 | 0.043417085174 | 0.6 | PRRT2 FRRS1L PGAP3 | Interictal epileptiform activity |
| HP:0025373 | 0.044850219801 | 0.6 | PRRT2 FRRS1L PGAP3 | Interictal EEG abnormality |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TBRG4 | FRRS1L | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PGAP3 | TBRG4 | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| PRRT2 | TBRG4 | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| BZW1 | TBRG4 | 0.953 | 0.206 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only |
Related Complexes