hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01941.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GAA | Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase] | 5 | UniProt NCBI |
| MANEAL | Glycoprotein endo-alpha-1,2-mannosidase-like protein (EC 3.2.1.-) | 3 | UniProt NCBI |
| LARGE1 | Xylosyl- and glucuronyltransferase LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A) (Glycosyltransferase-like protein) (LARGE xylosyl- and glucuronyltransferase 1) [Includes: Alpha-1,3-xylosyltransferase LARGE1 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE1 (EC 2.4.1.-)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5083627 | 0.0499419797295 | 0.5 | LARGE1 | Defective LARGE causes MDDGA6 and MDDGB6 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LARGE1 | GAA | 0.969 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MANEAL | GAA | 0.966 | 0.012 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| LARGE1 | MANEAL | 0.201 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes