hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01965.1
Complex Portal: CPX-24826
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAGEA2 | Melanoma-associated antigen 2 (Cancer/testis antigen 1.2) (CT1.2) (MAGE-2 antigen) | 5 | UniProt NCBI |
| GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha (DNA damage-inducible transcript 1 protein) (DDIT-1) | 5 | UniProt NCBI |
| OAT | Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine delta-aminotransferase) (Ornithine--oxo-acid aminotransferase) [Cleaved into: Ornithine aminotransferase, hepatic form; Ornithine aminotransferase, renal form] | 5 | UniProt NCBI |
| GZMH | Granzyme H (EC 3.4.21.-) (CCP-X) (Cathepsin G-like 2) (CTSGL2) (Cytotoxic T-lymphocyte proteinase) (Cytotoxic serine protease C) (CSP-C) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5190 | 0.0413734636003 | 0.333333333333 | OAT | Creatine pathway |
| CORUM:5544 | 0.0499402709677 | 0.333333333333 | GADD45A | CDC2-PCNA-CCNB1-GADD45A complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MAGEA2 | GZMH | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GADD45A | GZMH | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| OAT | GZMH | 0.959 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MAGEA2 | OAT | 0.262 | bioplex3_WMM WMM_only | ||
| GADD45A | MAGEA2 | 0.046 | bioplex3_WMM WMM_only | ||
| GADD45A | OAT | 0.018 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes