hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_01994.1
Complex Portal: CPX-21869
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GPRIN1 | G protein-regulated inducer of neurite outgrowth 1 (GRIN1) | 4 | UniProt NCBI |
| SLC6A1 | Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1) | 5 | UniProt NCBI |
| VTN | Vitronectin (VN) (S-protein) (Serum-spreading factor) (V75) [Cleaved into: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin-B] | 5 | UniProt NCBI |
| ISOC1 | Isochorismatase domain-containing protein 1 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0090992 | 0.0277669837126 | 0.5 | GPRIN1 SLC6A1 | cerebellum; molecular layer - neuropil[>=Medium] |
| CORUM:2826 | 0.049938562206 | 0.25 | VTN | ITGB3-ITGAV-VTN complex |
| REAC:R-HSA-888593 | 0.0499436884912 | 0.25 | SLC6A1 | Reuptake of GABA |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| VTN | ISOC1 | 0.979 | 0.0841075268817 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM | |
| GPRIN1 | VTN | 0.963 | 0.06 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SLC6A1 | VTN | 0.955 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| GPRIN1 | ISOC1 | 0.058 | 0.04 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes