hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_01995.1

Confidence: Extremely High

Genename	Protein Name	Uniprot Annotation Score	Links
ACTR5	Actin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16)	5	UniProt NCBI
INO80	Chromatin-remodeling ATPase INO80 (hINO80) (EC 3.6.4.-) (DNA helicase-related INO80 complex homolog 1) (DNA helicase-related protein INO80) (INO80 complex subunit A)	5	UniProt NCBI
TBRG1	Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2)	5	UniProt NCBI
INO80E	INO80 complex subunit E (Coiled-coil domain-containing protein 95)	5	UniProt NCBI
INO80B	INO80 complex subunit B (High mobility group AT-hook 1-like 4) (IES2 homolog) (hIes2) (PAP-1-associated protein 1) (PAPA-1) (Zinc finger HIT domain-containing protein 4)	5	UniProt NCBI
INO80D	INO80 complex subunit D	5	UniProt NCBI
YY1	Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1)	5	UniProt NCBI
MCRS1	Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle-regulated factor p78) (INO80 complex subunit J) (MCRS2)	5	UniProt NCBI
ACTR8	Actin-related protein 8 (hArp8) (INO80 complex subunit N)	5	UniProt NCBI
INO80C	INO80 complex subunit C (IES6 homolog) (hIes6)	5	UniProt NCBI
NFRKB	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B) (INO80 complex subunit G)	5	UniProt NCBI
TFPT	TCF3 fusion partner (INO80 complex subunit F) (Protein FB1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:302	9.60380741118e-27	0.818181818182	ACTR8 INO80B INO80C ACTR5 INO80 INO80E MCRS1 NFRKB INO80D	INO80 chromatin remodeling complex
GO:1904507	1.35174623237e-26	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of telomere maintenance in response to DNA damage
GO:0031011	3.60443217729e-26	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	Ino80 complex
GO:0060382	8.75307592766e-26	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of DNA strand elongation
GO:1904505	1.969319442e-25	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of telomere maintenance in response to DNA damage
REAC:R-HSA-5696394	1.10097320348e-23	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	DNA Damage Recognition in GG-NER
GO:0043247	3.79460402764e-23	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	telomere maintenance in response to DNA damage
GO:0097346	3.79460402764e-23	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	INO80-type complex
GO:0022616	1.56579741468e-21	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	DNA strand elongation
REAC:R-HSA-5696399	5.64888503997e-20	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	Global Genome Nucleotide Excision Repair (GG-NER)
KEGG:03082	1.19100721343e-19	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	ATP-dependent chromatin remodeling
REAC:R-HSA-5689603	1.49184577564e-19	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	UCH proteinases
GO:0045995	2.34247666287e-19	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of embryonic development
REAC:R-HSA-5696398	8.97898732377e-19	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	Nucleotide Excision Repair
GO:0032206	1.11268896175e-18	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of telomere maintenance
GO:0070603	3.23018980622e-17	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	SWI/SNF superfamily-type complex
GO:0006275	6.27179353888e-17	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of DNA replication
GO:0032204	7.75068461431e-17	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of telomere maintenance
GO:2001252	1.29128438796e-16	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of chromosome organization
GO:0006260	2.70201799224e-16	1.0	ACTR8 INO80B INO80C TBRG1 ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	DNA replication
GO:0045739	5.1904422292e-16	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of DNA repair
GO:1904949	2.37926511628e-15	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	ATPase complex
GO:0000723	3.1890778956e-15	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	telomere maintenance
REAC:R-HSA-5688426	4.83208134674e-15	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	Deubiquitination
GO:0032200	2.26282550315e-14	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	telomere organization
GO:0000228	2.26282550315e-14	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	nuclear chromosome
REAC:R-HSA-73894	3.91520429429e-14	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	DNA Repair
GO:0006282	8.12556826192e-14	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of DNA repair
GO:0033044	4.34539334944e-13	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of chromosome organization
GO:0051054	6.1458165778e-13	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of DNA metabolic process
GO:0010638	9.24396910085e-11	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of organelle organization
GO:0080135	1.02411971704e-10	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of cellular response to stress
GO:0006338	1.05051575524e-10	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	chromatin remodeling
GO:0009790	1.35018545426e-10	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	embryo development
GO:0051052	1.68340350534e-10	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of DNA metabolic process
GO:0006259	3.71908249606e-10	1.0	ACTR8 INO80B INO80C TBRG1 ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	DNA metabolic process
GO:0006325	4.15309964273e-10	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	chromatin organization
GO:0006281	7.7359532368e-10	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	DNA repair
GO:0051726	7.9209560551e-10	1.0	ACTR8 INO80B INO80C TBRG1 ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of cell cycle
GO:0051276	1.11702382493e-09	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	chromosome organization
GO:0071824	1.8209732459e-09	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	protein-DNA complex organization
GO:0006974	4.0554854618e-08	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	DNA damage response
REAC:R-HSA-597592	4.61317433403e-08	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	Post-translational protein modification
GO:0051130	8.06190882551e-08	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of cellular component organization
GO:0007049	9.07053460973e-08	1.0	ACTR8 INO80B INO80C TBRG1 ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	cell cycle
GO:2000026	1.19725512779e-07	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of multicellular organismal development
GO:0033043	3.80137847221e-07	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of organelle organization
GO:0080134	6.95572549481e-07	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of response to stress
GO:0000785	8.38273889908e-07	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	chromatin
REAC:R-HSA-392499	1.18319641032e-06	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	Metabolism of proteins
GO:0032993	1.50927380659e-06	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	protein-DNA complex
GO:0045893	1.82807385589e-06	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of DNA-templated transcription
GO:1902680	1.88078523862e-06	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of RNA biosynthetic process
GO:0140513	3.03987191608e-06	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	nuclear protein-containing complex
GO:0051254	5.69834927497e-06	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of RNA metabolic process
GO:0033554	1.40722559454e-05	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	cellular response to stress
GO:0045935	2.13153978443e-05	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of nucleobase-containing compound metabolic process
GO:0005694	3.107722397e-05	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	chromosome
GO:0050793	4.02936066896e-05	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of developmental process
GO:1902494	7.56872932336e-05	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	catalytic complex
GO:0048584	8.55623524134e-05	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of response to stimulus
GO:0043933	0.000170115208244	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	protein-containing complex organization
GO:0010557	0.000181638435841	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of macromolecule biosynthetic process
GO:0051128	0.000216710723583	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of cellular component organization
GO:0031328	0.000243352110076	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of cellular biosynthetic process
GO:0009891	0.000259225099621	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of biosynthetic process
GO:0051239	0.000371452254095	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of multicellular organismal process
GO:0051173	0.00141607801033	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of nitrogen compound metabolic process
GO:0031325	0.00357294269007	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of cellular metabolic process
GO:0006355	0.00451084211889	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of DNA-templated transcription
GO:2001141	0.00478749411208	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of RNA biosynthetic process
GO:0010604	0.00480782478495	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of macromolecule metabolic process
GO:0006351	0.0071899107241	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	DNA-templated transcription
GO:0032774	0.00798646080955	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	RNA biosynthetic process
GO:0007275	0.00811578346381	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	multicellular organism development
GO:0006950	0.00911090214581	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	response to stress
GO:0005654	0.0105448660706	1.0	ACTR8 INO80B INO80C TBRG1 ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	nucleoplasm
CORUM:5386	0.0110053190222	0.181818181818	MCRS1 INO80C	MLL1-WDR5 complex
GO:0009893	0.0115687276002	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	positive regulation of metabolic process
GO:0090304	0.0119029444692	1.0	ACTR8 INO80B INO80C TBRG1 ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	nucleic acid metabolic process
GO:0051252	0.0135387581616	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of RNA metabolic process
GO:0048583	0.0210705025756	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of response to stimulus
GO:0031981	0.0214587900711	1.0	ACTR8 INO80B INO80C TBRG1 ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	nuclear lumen
GO:0006996	0.0251340410919	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	organelle organization
HPA:0010013	0.0268442203938	0.363636363636	ACTR5 MCRS1 TFPT INO80E	adipose tissue; adipocytes[High]
GO:0034654	0.0273693774831	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	nucleobase-containing compound biosynthetic process
GO:0018130	0.0327201680984	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	heterocycle biosynthetic process
GO:0019438	0.0330622518626	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	aromatic compound biosynthetic process
GO:0019219	0.0331769891161	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	regulation of nucleobase-containing compound metabolic process
GO:0006139	0.0379532315546	1.0	ACTR8 INO80B INO80C TBRG1 ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	nucleobase-containing compound metabolic process
GO:1901362	0.0438918850918	0.909090909091	ACTR8 INO80B INO80C ACTR5 INO80 INO80E TFPT MCRS1 NFRKB INO80D	organic cyclic compound biosynthetic process

Edges

Protein 1	Protein 2	Score	ProteomeHD
ACTR5	INO80C	1.0	0.4
ACTR5	INO80E	1.0	0.23
ACTR5	INO80	1.0	0.198
INO80	INO80E	1.0	0.126
ACTR5	NFRKB	1.0	0.41
INO80E	NFRKB	1.0	0.074
INO80	NFRKB	1.0	0.4
TFPT	NFRKB	1.0	0.142
INO80C	NFRKB	1.0	0.26
INO80E	ACTR8	1.0	0.188
TFPT	INO80E	1.0	0.174
INO80	INO80C	1.0	0.248
INO80E	INO80C	1.0	0.166
INO80E	INO80D	1.0	0.086
TFPT	ACTR5	1.0	0.174
ACTR5	INO80D	1.0	0.184
ACTR8	INO80C	1.0	0.426
ACTR5	ACTR8	1.0	0.35
TFPT	INO80D	1.0	0.102
INO80	ACTR8	1.0	0.268
TFPT	INO80	1.0	0.124
INO80E	INO80B	1.0	0.12
INO80E	YY1	1.0	0.078
INO80E	MCRS1	1.0	0.22
ACTR8	NFRKB	0.999	0.254
TFPT	INO80C	0.999	0.184
INO80	YY1	0.999	0.204
YY1	INO80C	0.999	0.144
TFPT	INO80B	0.999	0.116
INO80D	ACTR8	0.999	0.148
INO80D	YY1	0.999	0.086
INO80B	ACTR8	0.999	0.206
INO80B	INO80C	0.999	0.146
INO80B	INO80D	0.999	0.082
INO80B	NFRKB	0.999	0.186
INO80	INO80B	0.999	0.2
TFPT	ACTR8	0.999	0.21
INO80B	YY1	0.999	0.23
TFPT	YY1	0.999	0.276
ACTR5	YY1	0.999	0.184
ACTR5	MCRS1	0.999	0.454
ACTR5	INO80B	0.999	0.26
INO80	INO80D	0.999	0.242
YY1	NFRKB	0.999	0.104
INO80D	INO80C	0.999	0.134
INO80D	NFRKB	0.998	0.098
TFPT	MCRS1	0.998	0.176
YY1	ACTR8	0.998	0.2
MCRS1	INO80C	0.998	0.228
INO80B	MCRS1	0.998	0.208
INO80D	MCRS1	0.998	0.23
YY1	MCRS1	0.997	0.256
MCRS1	NFRKB	0.997	0.4
INO80	MCRS1	0.997	0.474
MCRS1	ACTR8	0.996	0.48
TBRG1	INO80C	0.992	0.062
TBRG1	INO80E	0.992	0.13
ACTR5	TBRG1	0.99	0.118
TBRG1	INO80B	0.979	0.146
TBRG1	INO80D	0.978	0.166
INO80	TBRG1	0.977	0.13
TBRG1	ACTR8	0.976	0.154
TFPT	TBRG1	0.973	0.128
TBRG1	MCRS1	0.968	0.172
TBRG1	YY1	0.964	0.08
TBRG1	NFRKB	0.961	0.142

Related Complexes

Genename	Complexes
ACTR5	huMAP3_01995.1 huMAP3_14133.1
INO80	huMAP3_01995.1 huMAP3_14133.1
TBRG1	huMAP3_01995.1 huMAP3_14133.1
INO80E	huMAP3_01995.1 huMAP3_04952.1 huMAP3_14133.1
INO80B	huMAP3_01995.1 huMAP3_14133.1
INO80D	huMAP3_01995.1 huMAP3_14133.1
YY1	huMAP3_01995.1 huMAP3_14133.1
MCRS1	huMAP3_01995.1 huMAP3_03971.1 huMAP3_06050.1 huMAP3_08515.1 huMAP3_10050.1 huMAP3_11576.1 huMAP3_12676.1 huMAP3_14133.1 huMAP3_14284.1
ACTR8	huMAP3_01995.1 huMAP3_14133.1
INO80C	huMAP3_01995.1 huMAP3_14133.1
NFRKB	huMAP3_01995.1 huMAP3_14133.1
TFPT	huMAP3_00172.1 huMAP3_01995.1 huMAP3_06593.1 huMAP3_14133.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_01995.1