hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_02032.1

Complex Portal: CPX-14429

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
KLRD1	Natural killer cells antigen CD94 (KP43) (Killer cell lectin-like receptor subfamily D member 1) (NK cell receptor) (CD antigen CD94)	5	UniProt NCBI
OSBP	Oxysterol-binding protein 1	5	UniProt NCBI
OSBPL3	Oxysterol-binding protein-related protein 3 (ORP-3) (OSBP-related protein 3)	5	UniProt NCBI
OSBPL6	Oxysterol-binding protein-related protein 6 (ORP-6) (OSBP-related protein 6)	5	UniProt NCBI
PITPNM1	Membrane-associated phosphatidylinositol transfer protein 1 (Drosophila retinal degeneration B homolog) (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2)	5	UniProt NCBI
PITPNM3	Membrane-associated phosphatidylinositol transfer protein 3 (Phosphatidylinositol transfer protein, membrane-associated 3) (PITPnm 3) (Pyk2 N-terminal domain-interacting receptor 1) (NIR-1)	5	UniProt NCBI
VAPA	Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)	5	UniProt NCBI
ZFPL1	Zinc finger protein-like 1 (Zinc finger protein MCG4)	5	UniProt NCBI

Showing 1 to 8 of 8 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-556833	2.91817282149e-05	0.75	OSBPL6 VAPA OSBP PITPNM1 OSBPL3 PITPNM3	Metabolism of lipids
REAC:R-HSA-192105	3.03234516525e-05	0.375	OSBPL3 OSBPL6 OSBP	Synthesis of bile acids and bile salts
GO:0005319	7.59423271963e-05	0.625	PITPNM3 OSBPL6 OSBPL3 OSBP PITPNM1	lipid transporter activity
REAC:R-HSA-194068	8.31386651542e-05	0.375	OSBPL3 OSBPL6 OSBP	Bile acid and bile salt metabolism
REAC:R-HSA-1483226	0.000557398190654	0.25	PITPNM1 PITPNM3	Synthesis of PI
GO:0008610	0.00231375700448	0.75	OSBPL6 VAPA OSBP PITPNM1 OSBPL3 PITPNM3	lipid biosynthetic process
GO:0097038	0.00364711882004	0.375	OSBPL3 OSBPL6 OSBP	perinuclear endoplasmic reticulum
REAC:R-HSA-8957322	0.00655865508352	0.375	OSBPL3 OSBPL6 OSBP	Metabolism of steroids
GO:0006699	0.00824905178996	0.375	OSBPL3 OSBPL6 OSBP	bile acid biosynthetic process
GO:0015248	0.0139126682532	0.375	OSBPL3 OSBPL6 OSBP	sterol transporter activity

Showing 1 to 10 of 14 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
VAPA	OSBPL3	0.999	0.08		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
VAPA	ZFPL1	0.999	0.17		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM
VAPA	OSBPL6	0.999	0.140194444444		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
ZFPL1	OSBPL3	0.996	0.086		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
VAPA	OSBP	0.992	0.126		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
VAPA	PITPNM3	0.992			bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
OSBPL6	KLRD1	0.99			bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
OSBPL6	OSBPL3	0.985	0.082		bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only
VAPA	PITPNM1	0.983	0.11	structurally_consistent (dimer)	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ZFPL1	PITPNM3	0.979			bioplex3_WMM bioplex3_HCT116 WMM_only

Showing 1 to 10 of 25 entries

Related Complexes

Genename	Complexes
OSBPL3	huMAP3_00802.1 huMAP3_02032.1 huMAP3_03632.1 huMAP3_05790.1 huMAP3_07443.1 huMAP3_08362.1 huMAP3_08743.1 huMAP3_10464.1
ZFPL1	huMAP3_00750.1 huMAP3_00802.1 huMAP3_02032.1 huMAP3_05790.1 huMAP3_07443.1 huMAP3_08362.1 huMAP3_08743.1 huMAP3_10464.1 huMAP3_11833.1 huMAP3_12915.1
PITPNM1	huMAP3_00112.1 huMAP3_00443.1 huMAP3_00802.1 huMAP3_01422.1 huMAP3_02032.1 huMAP3_08362.1 huMAP3_08743.1 huMAP3_08783.1 huMAP3_10293.1 huMAP3_10464.1 huMAP3_11485.1 huMAP3_11506.1 huMAP3_13169.1 huMAP3_14473.1 huMAP3_14729.1
OSBP	huMAP3_00112.1 huMAP3_00802.1 huMAP3_00862.1 huMAP3_01422.1 huMAP3_02032.1 huMAP3_05953.1 huMAP3_08362.1 huMAP3_08743.1 huMAP3_08783.1 huMAP3_08942.1 huMAP3_10293.1 huMAP3_10464.1 huMAP3_11340.1 huMAP3_11485.1 huMAP3_12065.1 huMAP3_12460.1 huMAP3_12585.1 huMAP3_12614.1 huMAP3_12946.1 huMAP3_13964.1 huMAP3_14131.1 huMAP3_14473.1 huMAP3_14791.1 huMAP3_14847.1 huMAP3_15032.1
PITPNM3	huMAP3_00750.1 huMAP3_00802.1 huMAP3_02032.1 huMAP3_07443.1 huMAP3_08362.1 huMAP3_08743.1 huMAP3_08783.1 huMAP3_10464.1 huMAP3_11485.1 huMAP3_11506.1 huMAP3_11833.1 huMAP3_12915.1 huMAP3_13169.1 huMAP3_14473.1 huMAP3_14729.1
VAPA	huMAP3_00112.1 huMAP3_00802.1 huMAP3_01422.1 huMAP3_02032.1 huMAP3_05790.1 huMAP3_07443.1 huMAP3_08362.1 huMAP3_08743.1 huMAP3_08783.1 huMAP3_10293.1 huMAP3_10464.1 huMAP3_11485.1 huMAP3_11506.1 huMAP3_14473.1
OSBPL6	huMAP3_00802.1 huMAP3_02032.1 huMAP3_03632.1 huMAP3_05790.1 huMAP3_07443.1 huMAP3_08017.1 huMAP3_08362.1 huMAP3_08743.1 huMAP3_08783.1 huMAP3_10464.1 huMAP3_11944.1 huMAP3_12915.1
KLRD1	huMAP3_02032.1 huMAP3_03632.1 huMAP3_07443.1 huMAP3_08017.1 huMAP3_10464.1