hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02034.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| VAV2 | Guanine nucleotide exchange factor VAV2 (VAV-2) | 5 | UniProt NCBI |
| SHC2 | SHC-transforming protein 2 (Protein Sck) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2) | 5 | UniProt NCBI |
| RGPD3 | RanBP2-like and GRIP domain-containing protein 3 | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04650 | 0.00447126662273 | 0.666666666667 | SHC2 VAV2 | Natural killer cell mediated cytotoxicity |
| KEGG:04062 | 0.00727572841175 | 0.666666666667 | SHC2 VAV2 | Chemokine signaling pathway |
| WP:WP3929 | 0.00817907289077 | 0.666666666667 | SHC2 VAV2 | Chemokine signaling pathway |
| WP:WP2380 | 0.00845205977617 | 0.666666666667 | SHC2 VAV2 | Brain derived neurotrophic factor BDNF signaling pathway |
| KEGG:04510 | 0.0112688274497 | 0.666666666667 | SHC2 VAV2 | Focal adhesion |
| WP:WP306 | 0.0167214858931 | 0.666666666667 | SHC2 VAV2 | Focal adhesion |
| REAC:R-HSA-4420097 | 0.0254089329805 | 0.666666666667 | SHC2 VAV2 | VEGFA-VEGFR2 Pathway |
| REAC:R-HSA-194138 | 0.0303152414298 | 0.666666666667 | SHC2 VAV2 | Signaling by VEGF |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| VAV2 | SHC2 | 0.973 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| RGPD3 | SHC2 | 0.959 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RGPD3 | VAV2 | 0.1 | bioplex3_WMM WMM_only |
Related Complexes