hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02037.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ACBD7 | Acyl-CoA-binding domain-containing protein 7 | 3 | UniProt NCBI |
| RIDA | 2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) (14.5 kDa translational inhibitor protein) (hp14.5) (p14.5) (Heat-responsive protein 12) (Reactive intermediate imine deaminase A homolog) (Translation inhibitor L-PSP ribonuclease) (UK114 antigen homolog) | 5 | UniProt NCBI |
| ACOX1 | Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase) (Peroxisomal fatty acyl-CoA oxidase) (Straight-chain acyl-CoA oxidase) (SCOX) [Cleaved into: Peroxisomal acyl-CoA oxidase 1, A chain; Peroxisomal acyl-CoA oxidase 1, B chain; Peroxisomal acyl-CoA oxidase 1, C chain] | 5 | UniProt NCBI |
| ACAA1 | 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Acetyl-CoA acyltransferase) (EC 2.3.1.9) (Beta-ketothiolase) (Peroxisomal 3-oxoacyl-CoA thiolase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP1941 | 7.66076727379e-06 | 0.5 | ACOX1 ACAA1 | Peroxisomal beta oxidation of tetracosanoyl CoA |
| REAC:R-HSA-9033500 | 0.000153732433522 | 0.5 | ACOX1 ACAA1 | TYSND1 cleaves peroxisomal proteins |
| WP:WP4721 | 0.000306067313039 | 0.5 | ACOX1 ACAA1 | Eicosanoid metabolism via lipooxygenases LOX |
| KEGG:00592 | 0.00038319734907 | 0.5 | ACOX1 ACAA1 | alpha-Linolenic acid metabolism |
| KEGG:01040 | 0.000578341586214 | 0.5 | ACOX1 ACAA1 | Biosynthesis of unsaturated fatty acids |
| WP:WP4719 | 0.000644879603036 | 0.5 | ACOX1 ACAA1 | Eicosanoid metabolism via cyclooxygenases COX |
| KEGG:00071 | 0.00194963326435 | 0.5 | ACOX1 ACAA1 | Fatty acid degradation |
| KEGG:01212 | 0.0030591266514 | 0.5 | ACOX1 ACAA1 | Fatty acid metabolism |
| WP:WP3942 | 0.0035028118218 | 0.5 | ACOX1 ACAA1 | PPAR signaling pathway |
| KEGG:03320 | 0.00426927356048 | 0.5 | ACOX1 ACAA1 | PPAR signaling pathway |
| KEGG:04146 | 0.00502800723414 | 0.5 | ACOX1 ACAA1 | Peroxisome |
| GO:0016401 | 0.00842684400117 | 0.5 | ACOX1 ACAA1 | palmitoyl-CoA oxidase activity |
| REAC:R-HSA-9033241 | 0.0115164156767 | 0.5 | ACOX1 ACAA1 | Peroxisomal protein import |
| GO:0003997 | 0.0280843539964 | 0.5 | ACOX1 ACAA1 | acyl-CoA oxidase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ACBD7 | ACOX1 | 0.98 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ACOX1 | ACAA1 | 0.973 | 0.214 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RIDA | ACOX1 | 0.954 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| RIDA | ACAA1 | 0.017 | 0.032 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes