hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
IL36A	Interleukin-36 alpha (FIL1 epsilon) (Interleukin-1 epsilon) (IL-1 epsilon) (Interleukin-1 family member 6) (IL-1F6)	5	UniProt NCBI
RNF40	E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)	5	UniProt NCBI
RNF20	E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A)	5	UniProt NCBI
WAC	WW domain-containing adapter protein with coiled-coil	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:1165	1.53774525569e-05	0.5	RNF20 RNF40	RNF20-RNF40-UbE2E1 complex
REAC:R-HSA-8866654	3.47141671819e-05	0.75	RNF20 RNF40 WAC	E3 ubiquitin ligases ubiquitinate target proteins
REAC:R-HSA-8852135	9.06303437184e-05	0.75	RNF20 RNF40 WAC	Protein ubiquitination
WP:WP3878	0.0020866894725	0.5	RNF20 RNF40	ATM signaling in development and disease
GO:0033503	0.0168521501606	0.5	RNF20 RNF40	HULC complex

Protein 1	Protein 2	Score	ProteomeHD	Evidence
RNF40	WAC	1.0		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
RNF40	RNF20	0.998	0.938	bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only
RNF20	WAC	0.982		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM
IL36A	RNF40	0.965		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
IL36A	RNF20	0.964		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM