hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02057.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UBE2I | SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18) | 5 | UniProt NCBI |
| SUMO3 | Small ubiquitin-related modifier 3 (SUMO-3) (SMT3 homolog 1) (SUMO-2) (Ubiquitin-like protein SMT3A) (Smt3A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3065678 | 2.56314262819e-05 | 1.0 | SUMO3 UBE2I | SUMO is transferred from E1 to E2 (UBE2I, UBC9) |
| REAC:R-HSA-3215018 | 6.15154230766e-05 | 1.0 | SUMO3 UBE2I | Processing and activation of SUMO |
| REAC:R-HSA-4755510 | 7.68942788458e-05 | 1.0 | SUMO3 UBE2I | SUMOylation of immune response proteins |
| REAC:R-HSA-3232118 | 0.000179419983974 | 1.0 | SUMO3 UBE2I | SUMOylation of transcription factors |
| REAC:R-HSA-4090294 | 0.00023239159829 | 1.0 | SUMO3 UBE2I | SUMOylation of intracellular receptors |
| KEGG:03013 | 0.000820976957091 | 1.0 | SUMO3 UBE2I | Nucleocytoplasmic transport |
| REAC:R-HSA-3899300 | 0.00120125951175 | 1.0 | SUMO3 UBE2I | SUMOylation of transcription cofactors |
| REAC:R-HSA-5696395 | 0.00147124386858 | 1.0 | SUMO3 UBE2I | Formation of Incision Complex in GG-NER |
| REAC:R-HSA-4615885 | 0.00147124386858 | 1.0 | SUMO3 UBE2I | SUMOylation of DNA replication proteins |
| REAC:R-HSA-4551638 | 0.00366529395832 | 1.0 | SUMO3 UBE2I | SUMOylation of chromatin organization proteins |
| REAC:R-HSA-3108214 | 0.00424627295404 | 1.0 | SUMO3 UBE2I | SUMOylation of DNA damage response and repair proteins |
| REAC:R-HSA-5696399 | 0.00581491624249 | 1.0 | SUMO3 UBE2I | Global Genome Nucleotide Excision Repair (GG-NER) |
| REAC:R-HSA-5696398 | 0.0098732254038 | 1.0 | SUMO3 UBE2I | Nucleotide Excision Repair |
| REAC:R-HSA-3108232 | 0.0211937720117 | 1.0 | SUMO3 UBE2I | SUMO E3 ligases SUMOylate target proteins |
| REAC:R-HSA-2990846 | 0.0225607814134 | 1.0 | SUMO3 UBE2I | SUMOylation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| UBE2I | SUMO3 | 0.988 | 0.142 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM bioplex3_HCT116 gupta_WMM fraction |
Related Complexes