hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02084.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| C9orf72 | Guanine nucleotide exchange factor C9orf72 | 5 | UniProt NCBI |
| SMCR8 | Guanine nucleotide exchange protein SMCR8 (Smith-Magenis syndrome chromosomal region candidate gene 8 protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7064 | 1.70876175213e-06 | 1.0 | SMCR8 C9orf72 | C9orf72-SMCR8 complex |
| CORUM:7063 | 5.12628525639e-06 | 1.0 | SMCR8 C9orf72 | C9orf72-SMCR8-WDR41 complex |
| CORUM:7065 | 3.58839967947e-05 | 1.0 | SMCR8 C9orf72 | WDR41-(C9orf72-SMCR8)-(FIP200-ULK1-ATG13-ATG101) complex |
| KEGG:04140 | 0.00196546760618 | 1.0 | SMCR8 C9orf72 | Autophagy - animal |
| WP:WP5381 | 0.00414144818765 | 1.0 | SMCR8 C9orf72 | Smith Magenis and Potocki Lupski syndrome copy number variation |
| KEGG:05014 | 0.00850662183301 | 1.0 | SMCR8 C9orf72 | Amyotrophic lateral sclerosis |
| KEGG:05022 | 0.0138982457502 | 1.0 | SMCR8 C9orf72 | Pathways of neurodegeneration - multiple diseases |
| GO:1990316 | 0.016855225923 | 1.0 | SMCR8 C9orf72 | Atg1/ULK1 kinase complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| C9orf72 | SMCR8 | 0.957 | 0.21 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| C9orf72 | huMAP3_02084.1 huMAP3_11838.1 huMAP3_12683.1 huMAP3_14493.1 |
| SMCR8 | huMAP3_02084.1 huMAP3_15205.1 |