hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_02084.1

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
C9orf72	Guanine nucleotide exchange factor C9orf72	5	UniProt NCBI
SMCR8	Guanine nucleotide exchange protein SMCR8 (Smith-Magenis syndrome chromosomal region candidate gene 8 protein)	5	UniProt NCBI

Showing 1 to 2 of 2 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:7064	1.70876175213e-06	1.0	C9orf72 SMCR8	C9orf72-SMCR8 complex
CORUM:7063	5.12628525639e-06	1.0	C9orf72 SMCR8	C9orf72-SMCR8-WDR41 complex
CORUM:7065	3.58839967947e-05	1.0	C9orf72 SMCR8	WDR41-(C9orf72-SMCR8)-(FIP200-ULK1-ATG13-ATG101) complex
KEGG:04140	0.00196546760618	1.0	C9orf72 SMCR8	Autophagy - animal
WP:WP5381	0.00414144818765	1.0	C9orf72 SMCR8	Smith Magenis and Potocki Lupski syndrome copy number variation
KEGG:05014	0.00850662183301	1.0	C9orf72 SMCR8	Amyotrophic lateral sclerosis
KEGG:05022	0.0138982457502	1.0	C9orf72 SMCR8	Pathways of neurodegeneration - multiple diseases
GO:1990316	0.016855225923	1.0	C9orf72 SMCR8	Atg1/ULK1 kinase complex

Showing 1 to 8 of 8 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
C9orf72	SMCR8	0.957	0.21	bioplex3_HEK293 bioplex3_WMM WMM_only

Showing 1 to 1 of 1 entries

Related Complexes

Genename	Complexes
C9orf72	huMAP3_02084.1 huMAP3_11838.1 huMAP3_12683.1 huMAP3_14493.1
SMCR8	huMAP3_02084.1 huMAP3_15205.1