hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02086.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT) | 5 | UniProt NCBI |
| PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1 (PMA-induced protein 1) (Immediate-early-response protein APR) (Protein Noxa) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3614 | 0.000238782367243 | 1.0 | MCL1 PMAIP1 | Photodynamic therapy induced HIF 1 survival signaling |
| WP:WP254 | 0.00111857408398 | 1.0 | MCL1 PMAIP1 | Apoptosis |
| KEGG:04210 | 0.00116074761854 | 1.0 | MCL1 PMAIP1 | Apoptosis |
| WP:WP1772 | 0.00127818796583 | 1.0 | MCL1 PMAIP1 | Apoptosis modulation and signaling |
| WP:WP4399 | 0.0186595012434 | 0.5 | MCL1 | MicroRNA network associated with chronic lymphocytic leukemia |
| GO:0097136 | 0.0257510396046 | 1.0 | MCL1 PMAIP1 | Bcl-2 family protein complex |
| CORUM:5823 | 0.0499419797295 | 0.5 | MCL1 | MCL1-BAK1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MCL1 | PMAIP1 | 0.999 | 0.108 | bioplex3_HEK293 bioplex () bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| MCL1 | huMAP3_02086.1 huMAP3_10695.1 huMAP3_11267.1 |
| PMAIP1 | huMAP3_02086.1 huMAP3_10695.1 huMAP3_11267.1 |