hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02109.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARL2BP | ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein) (ARL2-binding protein) (Binder of ARF2 protein 1) | 5 | UniProt NCBI |
| ARL3 | ADP-ribosylation factor-like protein 3 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4803 | 0.00514595155073 | 1.0 | ARL2BP ARL3 | Ciliopathies |
| HP:0007675 | 0.00873519007688 | 1.0 | ARL2BP ARL3 | Progressive night blindness |
| HP:0030786 | 0.00973994198714 | 1.0 | ARL2BP ARL3 | Photopsia |
| HP:0007994 | 0.00999967377346 | 1.0 | ARL2BP ARL3 | Peripheral visual field loss |
| HP:0007787 | 0.0113495955576 | 1.0 | ARL2BP ARL3 | Posterior subcapsular cataract |
| HP:0007737 | 0.0127849554294 | 1.0 | ARL2BP ARL3 | Bone spicule pigmentation of the retina |
| HP:0000563 | 0.0130822799743 | 1.0 | ARL2BP ARL3 | Keratoconus |
| HP:0000523 | 0.0136871816346 | 1.0 | ARL2BP ARL3 | Subcapsular cataract |
| HP:0100692 | 0.0139947587499 | 1.0 | ARL2BP ARL3 | Increased corneal curvature |
| HP:0100689 | 0.0143057533888 | 1.0 | ARL2BP ARL3 | Decreased corneal thickness |
| HP:0001696 | 0.0146201655512 | 1.0 | ARL2BP ARL3 | Situs inversus totalis |
| HP:0011534 | 0.0152592424465 | 1.0 | ARL2BP ARL3 | Abnormal spatial orientation of the cardiac segments |
| HP:0011486 | 0.0159119894358 | 1.0 | ARL2BP ARL3 | Abnormality of corneal thickness |
| HP:0007843 | 0.0176036635704 | 1.0 | ARL2BP ARL3 | Attenuation of retinal blood vessels |
| HP:0001133 | 0.0208639809935 | 1.0 | ARL2BP ARL3 | Constriction of peripheral visual field |
| HP:0001651 | 0.0208639809935 | 1.0 | ARL2BP ARL3 | Dextrocardia |
| HP:0004307 | 0.0212433261025 | 1.0 | ARL2BP ARL3 | Abnormal anatomic location of the heart |
| HP:0000842 | 0.0227948817734 | 1.0 | ARL2BP ARL3 | Hyperinsulinemia |
| HP:0040214 | 0.0252247409849 | 1.0 | ARL2BP ARL3 | Abnormal circulating insulin concentration |
| HPA:0410563 | 0.0263823282362 | 0.5 | ARL3 | retina; limiting membrane[High] |
| HPA:0411243 | 0.0439675380582 | 0.5 | ARL3 | retina; inner plexiform layer[High] |
| HP:0000580 | 0.0440177027348 | 1.0 | ARL2BP ARL3 | Pigmentary retinopathy |
| HP:0000512 | 0.0473702932925 | 1.0 | ARL2BP ARL3 | Abnormal electroretinogram |
| HP:0001103 | 0.0490927251387 | 1.0 | ARL2BP ARL3 | Abnormal macular morphology |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ARL3 | ARL2BP | 0.99 | 0.038 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only |
Related Complexes