hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02159.1
Complex Portal: CPX-22920
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ATRIP | ATR-interacting protein (ATM and Rad3-related-interacting protein) | 5 | UniProt NCBI |
| CD70 | CD70 antigen (CD27 ligand) (CD27-L) (Tumor necrosis factor ligand superfamily member 7) (CD antigen CD70) | 5 | UniProt NCBI |
| IFRD1 | Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4) | 4 | UniProt NCBI |
| MINPP1 | Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:265 | 0.049938562206 | 0.25 | ATRIP | ATR-ATRIP complex |
| REAC:R-HSA-1855231 | 0.0499436884912 | 0.25 | MINPP1 | Synthesis of IPs in the ER lumen |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MINPP1 | CD70 | 0.996 | 0.062 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ATRIP | CD70 | 0.991 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| IFRD1 | CD70 | 0.977 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MINPP1 | ATRIP | 0.324 | 0.046 | bioplex3_WMM WMM_only | |
| IFRD1 | ATRIP | 0.165 | 0.0831612903226 | bioplex_WMM bioplex3_WMM WMM_only | |
| IFRD1 | MINPP1 | 0.042 | 0.044 | bioplex3_WMM WMM_only |
Related Complexes