hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02170.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
DBF4 | Protein DBF4 homolog A (Activator of S phase kinase) (Chiffon homolog A) (DBF4-type zinc finger-containing protein 1) | 5 | UniProt   NCBI |
CDC7 | Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  CORUM:947 | 1.70876175213e-06 | 1.0 | DBF4 CDC7 | CDC7-DBF7 complex |
  WP:WP466 | 0.00036647347272 | 1.0 | DBF4 CDC7 | DNA replication |
  REAC:R-HSA-68962 | 0.000902226205124 | 1.0 | DBF4 CDC7 | Activation of the pre-replicative complex |
  REAC:R-HSA-176187 | 0.00107651990384 | 1.0 | DBF4 CDC7 | Activation of ATR in response to replication stress |
  KEGG:04110 | 0.00184110178991 | 1.0 | DBF4 CDC7 | Cell cycle |
  WP:WP179 | 0.00283899891178 | 1.0 | DBF4 CDC7 | Cell cycle |
  GO:0010571 | 0.00702301080125 | 1.0 | DBF4 CDC7 | positive regulation of nuclear cell cycle DNA replication |
  GO:0033262 | 0.0131096201623 | 1.0 | DBF4 CDC7 | regulation of nuclear cell cycle DNA replication |
  REAC:R-HSA-69206 | 0.0143279672916 | 1.0 | DBF4 CDC7 | G1/S Transition |
  REAC:R-HSA-69002 | 0.0183367223621 | 1.0 | DBF4 CDC7 | DNA Replication Pre-Initiation |
  REAC:R-HSA-453279 | 0.0183367223621 | 1.0 | DBF4 CDC7 | Mitotic G1 phase and G1/S transition |
  REAC:R-HSA-69481 | 0.0214637563685 | 1.0 | DBF4 CDC7 | G2/M Checkpoints |
  REAC:R-HSA-69306 | 0.0257185731313 | 1.0 | DBF4 CDC7 | DNA Replication |
  GO:2000105 | 0.0257510396046 | 1.0 | DBF4 CDC7 | positive regulation of DNA-templated DNA replication |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 DBF4 |  CDC7 | 0.998 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
Related Complexes
Genename | Complexes |
---|---|
DBF4 | huMAP3_02170.1 huMAP3_13036.1 |
CDC7 | huMAP3_02170.1 huMAP3_13036.1 |