hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02171.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UFL1 | E3 UFM1-protein ligase 1 (EC 2.3.2.-) (E3 UFM1-protein transferase 1) (Multiple alpha-helix protein located at ER) (Novel LZAP-binding protein) (Regulator of C53/LZAP and DDRGK1) | 5 | UniProt NCBI |
| DDRGK1 | DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1903895 | 0.0028092043205 | 1.0 | UFL1 DDRGK1 | negative regulation of IRE1-mediated unfolded protein response |
| GO:1990564 | 0.00468200720083 | 1.0 | UFL1 DDRGK1 | protein polyufmylation |
| GO:1990592 | 0.00468200720083 | 1.0 | UFL1 DDRGK1 | protein K69-linked ufmylation |
| GO:0071569 | 0.00702301080125 | 1.0 | UFL1 DDRGK1 | protein ufmylation |
| GO:1900102 | 0.0365196561665 | 1.0 | UFL1 DDRGK1 | negative regulation of endoplasmic reticulum unfolded protein response |
| GO:1903894 | 0.0426062655276 | 1.0 | UFL1 DDRGK1 | regulation of IRE1-mediated unfolded protein response |
| HP:0008418 | 0.0499436884913 | 0.5 | DDRGK1 | Squared-off platyspondyly |
| HP:0008463 | 0.0499436884913 | 0.5 | DDRGK1 | Central vertebral hypoplasia |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| UFL1 | DDRGK1 | 1.0 | 0.94 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| UFL1 | huMAP3_02171.1 huMAP3_03937.1 huMAP3_07327.1 huMAP3_08805.1 huMAP3_12534.1 huMAP3_14075.1 |
| DDRGK1 | huMAP3_02171.1 huMAP3_03937.1 huMAP3_07327.1 huMAP3_08805.1 huMAP3_12534.1 huMAP3_14075.1 |