hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02172.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
ZNF408 | Zinc finger protein 408 (PR domain zinc finger protein 17) | 5 | UniProt   NCBI |
CDKN2A | Tumor suppressor ARF (Alternative reading frame) (ARF) (Cyclin-dependent kinase inhibitor 2A) (p14ARF) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-9646303 | 0.0249718442457 | 0.5 | CDKN2A | Evasion of Oncogene Induced Senescence Due to p14ARF Defects |
  REAC:R-HSA-9646304 | 0.0249718442457 | 0.5 | CDKN2A | Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects |
  CORUM:1642 | 0.0249718442457 | 0.5 | CDKN2A | p16-cyclin D2-CDK4 complex |
  REAC:R-HSA-9645722 | 0.0499419797295 | 0.5 | CDKN2A | Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function |
  REAC:R-HSA-9630791 | 0.0499419797295 | 0.5 | CDKN2A | Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 |
  REAC:R-HSA-9632697 | 0.0499419797295 | 0.5 | CDKN2A | Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 CDKN2A |  ZNF408 | 0.98 |            | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex3_WMM     |
Related Complexes
Genename | Complexes |
---|---|
ZNF408 | huMAP3_02172.1 huMAP3_12377.1 huMAP3_13566.1 huMAP3_14892.1 |
CDKN2A | huMAP3_01523.1 huMAP3_02172.1 huMAP3_09622.1 huMAP3_10449.1 huMAP3_14722.1 huMAP3_14892.1 |