hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_02172.1

Complex Portal: CPX-16342

Confidence: Extremely High

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Genename	Protein Name	Uniprot Annotation Score	Links
CDKN2A	Tumor suppressor ARF (Alternative reading frame) (ARF) (Cyclin-dependent kinase inhibitor 2A) (p14ARF)	5	UniProt NCBI
ZNF408	Zinc finger protein 408 (PR domain zinc finger protein 17)	5	UniProt NCBI

Showing 1 to 2 of 2 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-9646303	0.0249718442457	0.5	CDKN2A	Evasion of Oncogene Induced Senescence Due to p14ARF Defects
REAC:R-HSA-9646304	0.0249718442457	0.5	CDKN2A	Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects
CORUM:1642	0.0249718442457	0.5	CDKN2A	p16-cyclin D2-CDK4 complex
REAC:R-HSA-9645722	0.0499419797295	0.5	CDKN2A	Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function
REAC:R-HSA-9630791	0.0499419797295	0.5	CDKN2A	Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4
REAC:R-HSA-9632697	0.0499419797295	0.5	CDKN2A	Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4

Showing 1 to 6 of 6 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
CDKN2A	ZNF408	0.98			hein_WMM bioplex3_HEK293 bioplex () bioplex3_WMM

Showing 1 to 1 of 1 entries

Related Complexes

Genename	Complexes
ZNF408	huMAP3_02172.1 huMAP3_12377.1 huMAP3_13566.1 huMAP3_14892.1
CDKN2A	huMAP3_01523.1 huMAP3_02172.1 huMAP3_09622.1 huMAP3_10449.1 huMAP3_14722.1 huMAP3_14892.1