hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02180.1
Complex Portal: CPX-12546
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IKZF2 | Zinc finger protein Helios (Ikaros family zinc finger protein 2) | 5 | UniProt NCBI |
| IKZF1 | DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1) | 5 | UniProt NCBI |
| IKZF3 | Zinc finger protein Aiolos (Ikaros family zinc finger protein 3) | 5 | UniProt NCBI |
| IKZF4 | Zinc finger protein Eos (Ikaros family zinc finger protein 4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0010976 | 0.036003514982 | 0.5 | IKZF1 IKZF3 | B lymphocytopenia |
| CORUM:5441 | 0.049938562206 | 0.25 | IKZF4 | NRG1-IKZF4 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| IKZF3 | IKZF4 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| IKZF2 | IKZF1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| IKZF1 | IKZF4 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| IKZF1 | IKZF3 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| IKZF2 | IKZF4 | 0.797 | bioplex_WMM bioplex3_WMM WMM_only | ||
| IKZF2 | IKZF3 | 0.36 | 0.182 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes