hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_02182.1
Complex Portal: CPX-21276
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FZD3 | Frizzled-3 (Fz-3) (hFz3) | 5 | UniProt NCBI |
| OTUD6A | OTU domain-containing protein 6A (EC 3.4.19.12) (DUBA-2) | 5 | UniProt NCBI |
| GPR21 | Probable G-protein coupled receptor 21 | 3 | UniProt NCBI |
| FZD5 | Frizzled-5 (Fz-5) (hFz5) (FzE5) | 5 | UniProt NCBI |
| XKR8 | XK-related protein 8 (hXkr8) [Cleaved into: XK-related protein 8, processed form] | 5 | UniProt NCBI |
| SLC47A1 | Multidrug and toxin extrusion protein 1 (MATE-1) (hMATE-1) (Solute carrier family 47 member 1) | 5 | UniProt NCBI |
| SLC35B4 | Nucleotide sugar transporter SLC35B4 (Solute carrier family 35 member B4) (UDP-xylose and UDP-N-acetylglucosamine transporter) (YEA4 homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4150 | 0.00991981492579 | 0.285714285714 | FZD5 FZD3 | Wnt signaling in kidney disease |
| KEGG:05217 | 0.0150576821029 | 0.285714285714 | FZD5 FZD3 | Basal cell carcinoma |
| WP:WP3680 | 0.0300823189809 | 0.285714285714 | FZD5 FZD3 | Physico chemical features and toxicity associated pathways |
| KEGG:04916 | 0.0342858776489 | 0.285714285714 | FZD5 FZD3 | Melanogenesis |
| WP:WP4336 | 0.0473257570206 | 0.285714285714 | FZD5 FZD3 | ncRNAs involved in Wnt signaling in hepatocellular carcinoma |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| OTUD6A | GPR21 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| GPR21 | SLC35B4 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| GPR21 | FZD5 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| FZD3 | GPR21 | 0.966 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| GPR21 | SLC47A1 | 0.963 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| XKR8 | GPR21 | 0.961 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| OTUD6A | SLC35B4 | 0.557 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FZD5 | SLC35B4 | 0.557 | bioplex_WMM bioplex3_WMM WMM_only | ||
| OTUD6A | FZD5 | 0.557 | bioplex_WMM bioplex3_WMM WMM_only | ||
| XKR8 | SLC35B4 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only | ||
| XKR8 | OTUD6A | 0.502 | bioplex_WMM bioplex3_WMM WMM_only | ||
| XKR8 | FZD5 | 0.333 | bioplex_WMM bioplex3_WMM WMM_only | ||
| XKR8 | SLC47A1 | 0.327 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FZD5 | SLC47A1 | 0.304 | bioplex_WMM bioplex3_WMM WMM_only | ||
| XKR8 | FZD3 | 0.234 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FZD3 | SLC35B4 | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FZD3 | OTUD6A | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FZD3 | FZD5 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | ||
| FZD3 | SLC47A1 | 0.163 | bioplex_WMM bioplex3_WMM WMM_only | ||
| OTUD6A | SLC47A1 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SLC47A1 | SLC35B4 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes