hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02185.1
Complex Portal: CPX-16390
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] | 5 | UniProt NCBI |
| TMEM158 | Transmembrane protein 158 (40 kDa BINP-binding protein) (p40BBP) (Ras-induced senescence protein 1) | 3 | UniProt NCBI |
| GRIN1 | Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) | 5 | UniProt NCBI |
| HGSNAT | Heparan-alpha-glucosaminide N-acetyltransferase (EC 2.3.1.78) (Transmembrane protein 76) | 5 | UniProt NCBI |
| ASIC4 | Acid-sensing ion channel 4 (ASIC4) (Amiloride-sensitive cation channel 4) (Amiloride-sensitive cation channel 4, pituitary) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05017 | 0.0346393491085 | 0.4 | GRIN1 ERN1 | Spinocerebellar ataxia |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ERN1 | ASIC4 | 0.999 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GRIN1 | ASIC4 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TMEM158 | ASIC4 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HGSNAT | ASIC4 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| TMEM158 | GRIN1 | 0.902 | bioplex3_WMM WMM_only | ||
| ERN1 | GRIN1 | 0.675 | bioplex3_WMM WMM_only | ||
| ERN1 | TMEM158 | 0.427 | bioplex3_WMM WMM_only | ||
| TMEM158 | HGSNAT | 0.214 | bioplex3_WMM WMM_only | ||
| GRIN1 | HGSNAT | 0.108 | bioplex3_WMM WMM_only | ||
| ERN1 | HGSNAT | 0.042 | 0.062 | bioplex3_WMM WMM_only |
Related Complexes