hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02192.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ETNK2 | Ethanolamine kinase 2 (EKI 2) (EC 2.7.1.82) (Ethanolamine kinase-like protein) | 5 | UniProt NCBI |
| RGP1 | RAB6A-GEF complex partner protein 2 (Retrograde Golgi transport protein RGP1 homolog) | 5 | UniProt NCBI |
| GTSF1 | Gametocyte-specific factor 1 (Protein FAM112B) | 3 | UniProt NCBI |
| RIC1 | Guanine nucleotide exchange factor subunit RIC1 (Connexin-43-interacting protein of 150 kDa) (Protein RIC1 homolog) (RAB6A-GEF complex partner protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0034066 | 0.0028092043205 | 0.5 | RGP1 RIC1 | Ric1-Rgp1 guanyl-nucleotide exchange factor complex |
| REAC:R-HSA-6811438 | 0.00966180252737 | 0.5 | RGP1 RIC1 | Intra-Golgi traffic |
| REAC:R-HSA-6811440 | 0.0110375739361 | 0.5 | RGP1 RIC1 | Retrograde transport at the Trans-Golgi-Network |
| REAC:R-HSA-8876198 | 0.0329793636325 | 0.5 | RGP1 RIC1 | RAB GEFs exchange GTP for GDP on RABs |
| CORUM:7296 | 0.049938562206 | 0.25 | RGP1 | PRT1-RGP1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RGP1 | ETNK2 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RGP1 | GTSF1 | 0.987 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| RGP1 | RIC1 | 0.966 | 0.17 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes