hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_02246.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ITGA5 | Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain] | 5 | UniProt NCBI |
| TGM2 | Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Erythrocyte transglutaminase) (Heart G alpha(h)) (hhG alpha(h)) (Isopeptidase TGM2) (EC 3.4.-.-) (Protein G alpha(h)) (G(h)) (Protein-glutamine deamidase TGM2) (EC 3.5.1.44) (Protein-glutamine dopaminyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine histaminyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine noradrenalinyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine serotonyltransferase TGM2) (EC 2.3.1.-) (Tissue transglutaminase) (tTG) (tTgase) (Transglutaminase C) (TG(C)) (TGC) (TGase C) (Transglutaminase H) (TGase H) (Transglutaminase II) (TGase II) (Transglutaminase-2) (TG2) (TGase-2) (hTG2) | 5 | UniProt NCBI |
| PLA2G2E | Group IIE secretory phospholipase A2 (GIIE sPLA2) (sPLA2-IIE) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 2E) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2383 | 2.05032700758e-05 | 0.666666666667 | ITGA5 TGM2 | ITGA5-ITGB1-FN1-TGM2 complex |
| CORUM:2882 | 0.0249718442456 | 0.333333333333 | ITGA5 | ITGA5-ITGB3-COL6A3 complex |
| KEGG:03266 | 0.0390296209856 | 0.333333333333 | ITGA5 | Virion - Herpesvirus |
| CORUM:2242 | 0.0499402709677 | 0.333333333333 | TGM2 | TGM2-HD-CALM1 complex |
| CORUM:2243 | 0.0499402709677 | 0.333333333333 | TGM2 | TGM2-HD complex |
| CORUM:2375 | 0.0499402709677 | 0.333333333333 | TGM2 | FN1-TGM2 complex |
| CORUM:2376 | 0.0499402709677 | 0.333333333333 | TGM2 | ITGA2B-ITGB3-FN1-TGM2 complex |
| CORUM:2385 | 0.0499402709677 | 0.333333333333 | ITGA5 | ITGA5-ITGB4 complex |
| CORUM:3112 | 0.0499402709677 | 0.333333333333 | ITGA5 | ITGA5-ITGB1-SPP1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ITGA5 | TGM2 | 0.982 | 0.154 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| ITGA5 | PLA2G2E | 0.957 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes